ProtParam

User-provided sequence:

        10         20         30         40         50         60 
METRKDDMEK RNDKSEPLLL PENGSDVSEE ASWMVYLSTI IAVCGSYEFG TCVGYSAPTQ 

        70         80         90        100        110        120 
FGIMEELNLS YSQFSVFGSI LNMGAVLGAI TSGKISDFIG RKGAMRLSSV ISAIGWLIIY 

       130        140        150        160        170        180 
LAKGDVPLDF GRFLTGYGCG TLSFVVPVFI AEISPRKLRG ALATLNQLFI VIGLASMFLI 

       190        200        210        220        230        240 
GAVVNWRTLA LTGVAPCVVL FFGTWFIPES PRWLEMVGRH SDFEIALQKL RGPQANITRE 

       250        260        270        280        290        300 
AGEIQEYLAS LAHLPKATLM DLIDKKNIRF VIVGVGLMFF QQFVGINGVI FYAQQIFVSA 

       310        320        330        340        350        360 
GASPTLGSIL YSIEQVVLTA LGATLLIDRL GRRPLLMASA VGMLIGCLLI GNSFLLKAHG 

       370        380        390        400        410        420 
LALDIIPALA VSGVLVYIGS FSIGMGAIPW VIMSEIFPIN LKGTAGGLVT VVNWLSSWLV 

       430        440        450        460        470 
SFTFNFLMIW SPHGTFYVYG GVCVLAIIFI AKLVPETKGR TLEEIQAMMM 

References and documentation are available.

Number of amino acids: 470

Molecular weight: 51024.30

Theoretical pI: 6.46

Amino acid composition: 
Ala (A)  37	  7.9%
Arg (R)  17	  3.6%
Asn (N)  13	  2.8%
Asp (D)  12	  2.6%
Cys (C)   6	  1.3%
Gln (Q)  12	  2.6%
Glu (E)  21	  4.5%
Gly (G)  48	 10.2%
His (H)   4	  0.9%
Ile (I)  44	  9.4%
Leu (L)  58	 12.3%
Lys (K)  15	  3.2%
Met (M)  18	  3.8%
Phe (F)  29	  6.2%
Pro (P)  18	  3.8%
Ser (S)  36	  7.7%
Thr (T)  22	  4.7%
Trp (W)   9	  1.9%
Tyr (Y)  12	  2.6%
Val (V)  39	  8.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 33
Total number of positively charged residues (Arg + Lys): 32

Atomic composition:

Carbon      C	      2357
Hydrogen    H	      3708
Nitrogen    N	       578
Oxygen      O	       632
Sulfur      S	        24

Formula: C2357H3708N578O632S24
Total number of atoms: 7299

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    67755
Abs 0.1% (=1 g/l)   1.328, assuming all pairs of Cys residues form cystines


Ext. coefficient    67380
Abs 0.1% (=1 g/l)   1.321, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 29.19
This classifies the protein as stable.



Aliphatic index: 116.57

Grand average of hydropathicity (GRAVY): 0.665