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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
METSSNLSSM VRLNIGGKKF CTTIDTLTIR EPDSMLAAMF SGRHAMCQES KKGYVFIDRD

70 80 90 100 110 120
GKHFRHILNW LRDGVIPSLS DPDCSELLRE ADYYQLLGLK DGIKDSRKEV GEVEAELTRI

130 140 150 160 170 180
DIIKCIQTER VRFRGVNLSG IDLSKLDLSL VDFSYACLRN VFFSRTNLQC AKFRNADAEG

190 200 210 220 230 240
SIFHNAILRE CEFTSANLRG ALLAGTNLQS ANLQDACLVG CSFCGADLRT AHLQNADLTN

250 260 270 280 290
ANLEGANLEG ANLKGAKLSN ANFKGANLQR AYLRHVNLRE AVSPKPILGY


References and documentation are available.

Number of amino acids: 290 Molecular weight: 32101.63 Theoretical pI: 8.01
Amino acid composition: 
Ala (A) 26 9.0% Arg (R) 21 7.2% Asn (N) 20 6.9% Asp (D) 18 6.2% Cys (C) 10 3.4% Gln (Q) 8 2.8% Glu (E) 16 5.5% Gly (G) 21 7.2% His (H) 6 2.1% Ile (I) 15 5.2% Leu (L) 38 13.1% Lys (K) 15 5.2% Met (M) 5 1.7% Phe (F) 13 4.5% Pro (P) 5 1.7% Ser (S) 22 7.6% Thr (T) 12 4.1% Trp (W) 1 0.3% Tyr (Y) 6 2.1% Val (V) 12 4.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 34 Total number of positively charged residues (Arg + Lys): 36 Atomic composition: Carbon C 1398 Hydrogen H 2251 Nitrogen N 409 Oxygen O 427 Sulfur S 15 Formula: C1398H2251N409O427S15 Total number of atoms: 4500 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 15065 Abs 0.1% (=1 g/l) 0.469, assuming all pairs of Cys residues form cystines Ext. coefficient 14440 Abs 0.1% (=1 g/l) 0.450, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 34.74 This classifies the protein as stable. Aliphatic index: 92.24 Grand average of hydropathicity (GRAVY): -0.208