ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MFANVGFRTL RVSRGPLYGM FIVLFIGVLI AKFAGQMLID SETNFSHIIG SCSQIISFSK 

        70         80         90        100        110        120 
RTFYSSAKSG YQSNNSHGDA YSSGSQSGPF TYKTAVAFQP KDRDDLIYQK LKDSIRSPTG 

       130        140        150        160        170        180 
EDNYFVTSNN VHDIFAGVAD GVGGWAEHGY DSSAISRELC KKMDEISTAL AENSSKETLL 

       190        200        210        220        230        240 
TPKKIIGAAY AKIRDEKVVK VGGTTAIVAH FPSNGKLEVA NLGDSWCGVF RDSKLVFQTK 

       250        260        270        280        290        300 
FQTVGFNAPY QLSIIPEEML KEAERRGSKY ILNTPRDADE YSFQLKKKDI IILATDGVTD 

       310        320        330        340        350        360 
NIATDDIELF LKDNAARTND ELQLLSQKFV DNVVSLSKDP NYPSVFAQEI SKLTGKNYSG 

       370 
GKEDDITVVV VRVD 

References and documentation are available.

Number of amino acids: 374

Molecular weight: 41190.49

Theoretical pI: 6.03

Amino acid composition: 
Ala (A)  27	  7.2%
Arg (R)  14	  3.7%
Asn (N)  18	  4.8%
Asp (D)  28	  7.5%
Cys (C)   3	  0.8%
Gln (Q)  13	  3.5%
Glu (E)  18	  4.8%
Gly (G)  28	  7.5%
His (H)   5	  1.3%
Ile (I)  27	  7.2%
Leu (L)  26	  7.0%
Lys (K)  29	  7.8%
Met (M)   5	  1.3%
Phe (F)  21	  5.6%
Pro (P)  11	  2.9%
Ser (S)  37	  9.9%
Thr (T)  21	  5.6%
Trp (W)   2	  0.5%
Tyr (Y)  14	  3.7%
Val (V)  27	  7.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 46
Total number of positively charged residues (Arg + Lys): 43

Atomic composition:

Carbon      C	      1838
Hydrogen    H	      2880
Nitrogen    N	       488
Oxygen      O	       570
Sulfur      S	         8

Formula: C1838H2880N488O570S8
Total number of atoms: 5784

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    31985
Abs 0.1% (=1 g/l)   0.777, assuming all pairs of Cys residues form cystines


Ext. coefficient    31860
Abs 0.1% (=1 g/l)   0.773, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 30.83
This classifies the protein as stable.



Aliphatic index: 83.42

Grand average of hydropathicity (GRAVY): -0.258