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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MFCRKFKDLK ITGECPFSLL APGQVPKEPT EEVAGGSEGC QATLPICQYF PEKNAEGSLP

70 80 90 100 110 120
QRKTSRNRVY LHTLAESICK LIFPECERLN LALQRTLAKH KIEENRKSSE KEDLEKIIAE

130 140 150 160 170 180
EAIAAGAPVE ALKDSLGEEL FKICYEEDEH ILGVVGGTLK DFLNSFSTLL KQSSHCQEAE

190 200 210 220 230 240
RRGRLEDASI LCLDKDQDFL NVYYFFPKRT TALLLPGIIK AAARILYESH VEVSLMPPCF

250 260 270 280 290 300
RSDCTEFVNQ PYLLYSVHVK STKPSLSPGK PQSSLVIPAS LFCKTFPFHF MLDRDLAILQ

310 320 330 340 350 360
LGNGIRRLVN KRDFQGKPNF EEFFEILTPK INQTFSGIMT MLNMQFVIRV RRWDNSVKKS

370 380 390 400 410 420
SRVMDLKGQM IYIVESSAIL FLGSPCVDRL EDFTGRGLYL SDIPIHNALR DVVLIGEQAR

430 440 450 460 470 480
AQDGLKKRLG KLKATLEHAH QALEEEKKRT VDLLCSIFPS EVAQQLWQGQ IVQAKKFSEV

490 500 510 520 530 540
TMLFSDIVGF TAICSQCSPL QVITMLNALY TRFDQQCGEL DVYKVETIGD AYCVAGGLHR

550 560 570 580 590 600
ESDTHAVQIA LMALKMMELS NEVMSPHGEP IKMRIGLHSG SVFAGVVGVK MPRYCLFGNN

610 620 630 640 650 660
VTLANKFESC SVPRKINVSP TTYRLLKDCP GFVFTPRSRE ELPPNFPSDI PGICHFLDAY

670 680 690
HHQGPNSKPW FQDKDVEDGN ANFLGKASGV D


References and documentation are available.

Number of amino acids: 691 Molecular weight: 77573.59 Theoretical pI: 6.79
Amino acid composition: 
Ala (A) 42 6.1% Arg (R) 35 5.1% Asn (N) 24 3.5% Asp (D) 33 4.8% Cys (C) 22 3.2% Gln (Q) 30 4.3% Glu (E) 51 7.4% Gly (G) 43 6.2% His (H) 17 2.5% Ile (I) 39 5.6% Leu (L) 75 10.9% Lys (K) 47 6.8% Met (M) 16 2.3% Phe (F) 39 5.6% Pro (P) 38 5.5% Ser (S) 49 7.1% Thr (T) 29 4.2% Trp (W) 3 0.4% Tyr (Y) 16 2.3% Val (V) 43 6.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 84 Total number of positively charged residues (Arg + Lys): 82 Atomic composition: Carbon C 3465 Hydrogen H 5484 Nitrogen N 934 Oxygen O 1008 Sulfur S 38 Formula: C3465H5484N934O1008S38 Total number of atoms: 10929 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41715 Abs 0.1% (=1 g/l) 0.538, assuming all pairs of Cys residues form cystines Ext. coefficient 40340 Abs 0.1% (=1 g/l) 0.520, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 44.54 This classifies the protein as unstable. Aliphatic index: 88.47 Grand average of hydropathicity (GRAVY): -0.185