Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MFKKYKNQDL DMAFWWKKNP KTPSDYARLI IEQLNKFSSP SLTQDNKRKV QEECTKYLIG

70 80 90 100 110 120
TKHFIVGDTD PHPTPEAIDE LYTAMHRADV FYELLLHFVD LEFEARRECM LIFSICLGYS

130 140 150 160 170 180
KDNKFVTVDY LVSQPKTISL MLRTAEVALQ QKGCQDIFLT VGNMIIECIK YEQLCRIILK

190 200 210 220 230 240
DPQLWKFFEF AKLGNFEIST ESLQILSAAF TAHPKLVSKE FFSNEINIIR FIKCINKLMA

250 260 270 280 290 300
HGSYVTKRQS TKLLASLIVI RSNNALMNIY INSPENLKLI MTLMTDKSKN LQLEAFNVFK

310 320 330 340 350 360
VMVANPRKSK PVFDILVKNR DKLLTYFKTF GLDSQDSTFL DEREFIVQEI DSLPRIISST

370 380 390
TEVSNNNASS SNVASITSPS SVMNNQSSIL THSTSPDSR


References and documentation are available.

Number of amino acids: 399 Molecular weight: 45853.05 Theoretical pI: 8.64
Amino acid composition: 
Ala (A) 19 4.8% Arg (R) 15 3.8% Asn (N) 25 6.3% Asp (D) 21 5.3% Cys (C) 7 1.8% Gln (Q) 16 4.0% Glu (E) 23 5.8% Gly (G) 8 2.0% His (H) 7 1.8% Ile (I) 33 8.3% Leu (L) 41 10.3% Lys (K) 34 8.5% Met (M) 12 3.0% Phe (F) 25 6.3% Pro (P) 15 3.8% Ser (S) 38 9.5% Thr (T) 25 6.3% Trp (W) 3 0.8% Tyr (Y) 11 2.8% Val (V) 21 5.3% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 44 Total number of positively charged residues (Arg + Lys): 49 Atomic composition: Carbon C 2064 Hydrogen H 3272 Nitrogen N 536 Oxygen O 603 Sulfur S 19 Formula: C2064H3272N536O603S19 Total number of atoms: 6494 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 33265 Abs 0.1% (=1 g/l) 0.725, assuming all pairs of Cys residues form cystines Ext. coefficient 32890 Abs 0.1% (=1 g/l) 0.717, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 49.67 This classifies the protein as unstable. Aliphatic index: 92.36 Grand average of hydropathicity (GRAVY): -0.188