ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MFKRFSKKKE APEDPKNLIN IDKPIKELPA SIAIPKEKPL TGEQQKMYDE VLKHFSNPDL 

        70         80         90        100        110        120 
KVYTSEKNKS EDDLKPLEEE EKAWLTRECF LRYLRATKWV LKDCIDRITM TLAWRREFGI 

       130        140        150        160        170        180 
SHLGEEHGDK ITADLVAVEN ESGKQVILGY ENDARPILYL KPGRQNTKTS HRQVQHLVFM 

       190        200        210        220        230        240 
LERVIDFMPA GQDSLALLID FKDYPDVPKV PGNSKIPPIG VGKEVLHILQ THYPERLGKA 

       250        260        270        280        290        300 
LLTNIPWLAW TFLKLIHPFI DPLTREKLVF DEPFVKYVPK NELDSLYGGD LKFKYNHDVY 

       310        320        330        340        350 
WPALVETARE KRDHYFKRFQ SFGGIVGLSE VDLRGTHEKL LYPVKSESST V 

References and documentation are available.

Number of amino acids: 351

Molecular weight: 40713.98

Theoretical pI: 7.73

Amino acid composition: 
Ala (A)  15	  4.3%
Arg (R)  17	  4.8%
Asn (N)  11	  3.1%
Asp (D)  23	  6.6%
Cys (C)   2	  0.6%
Gln (Q)   9	  2.6%
Glu (E)  30	  8.5%
Gly (G)  18	  5.1%
His (H)  11	  3.1%
Ile (I)  20	  5.7%
Leu (L)  40	 11.4%
Lys (K)  37	 10.5%
Met (M)   5	  1.4%
Phe (F)  16	  4.6%
Pro (P)  24	  6.8%
Ser (S)  16	  4.6%
Thr (T)  16	  4.6%
Trp (W)   6	  1.7%
Tyr (Y)  13	  3.7%
Val (V)  22	  6.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 53
Total number of positively charged residues (Arg + Lys): 54

Atomic composition:

Carbon      C	      1862
Hydrogen    H	      2913
Nitrogen    N	       487
Oxygen      O	       523
Sulfur      S	         7

Formula: C1862H2913N487O523S7
Total number of atoms: 5792

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    52495
Abs 0.1% (=1 g/l)   1.289, assuming all pairs of Cys residues form cystines


Ext. coefficient    52370
Abs 0.1% (=1 g/l)   1.286, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.98
This classifies the protein as stable.



Aliphatic index: 89.12

Grand average of hydropathicity (GRAVY): -0.521