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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MFKSLFDAAQ NSTFKSPFTS VNCQSATPTS APTSTAVVTP TLKDVAPRQL TRNHNIAAAA

70 80 90 100 110 120
VAEGDSCEFG SNHYFLLCGL GGIISCGSTH TMVVPLDLVK CRLQVDPAKY KSVFTGFRIS

130 140 150 160 170 180
LAEEGVRGLA KGWAPTFIGY SMQGLCKFGL YEVFKKVYGD AIGEENAFLY RTGLYLAASA

190 200 210 220 230 240
SAEFFADIAL APMEAAKVKI QTTPGFAKTL REALPKMTAQ EGVTAFYKGL VPLWMRQIPY

250 260 270 280 290 300
TMMKFACFER TLELLYKYVV PKPRADCTKG EQLVVTFAAG YIAGVFCAIV SHPADTVVSK

310 320 330 340 350 360
LNQAKGASAL DVAKQLGWSG LWGGLVPRIV MIGTLTAAQW FIYDAVKVFL RMPRPPPPEM

370
PESLKKKLGV TGEQ


References and documentation are available.

Number of amino acids: 374 Molecular weight: 40553.33 Theoretical pI: 9.14
Amino acid composition: 
Ala (A) 44 11.8% Arg (R) 13 3.5% Asn (N) 7 1.9% Asp (D) 11 2.9% Cys (C) 9 2.4% Gln (Q) 13 3.5% Glu (E) 17 4.5% Gly (G) 30 8.0% His (H) 4 1.1% Ile (I) 14 3.7% Leu (L) 34 9.1% Lys (K) 26 7.0% Met (M) 11 2.9% Phe (F) 22 5.9% Pro (P) 23 6.1% Ser (S) 21 5.6% Thr (T) 27 7.2% Trp (W) 5 1.3% Tyr (Y) 13 3.5% Val (V) 30 8.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 28 Total number of positively charged residues (Arg + Lys): 39 Atomic composition: Carbon C 1848 Hydrogen H 2890 Nitrogen N 472 Oxygen O 512 Sulfur S 20 Formula: C1848H2890N472O512S20 Total number of atoms: 5742 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 47370 Abs 0.1% (=1 g/l) 1.168, assuming all pairs of Cys residues form cystines Ext. coefficient 46870 Abs 0.1% (=1 g/l) 1.156, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 31.29 This classifies the protein as stable. Aliphatic index: 85.08 Grand average of hydropathicity (GRAVY): 0.149