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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MFLIRLSRHN PSSFTLLTRR LHDQTISSSR LRDLYNFQSP PPLSSSASEN PDFNQKNNNK

70 80 90 100 110 120
KKPKPQYRPP SSLEGVKTVH SDLPFDFRFS YTESCSNVRP IGLREPKYSP FGPDRLDREW

130 140 150 160 170 180
TGVCAPAVNP KVESVDGVED PKLEEKRRKV REKIQGASLT EAERKFLVEL CQRNKTKRQV

190 200 210 220 230 240
NLGRDGLTHN MLNDVYNHWK HAEAVRVKCL GVPTLDMKNV IFHLEDKTFG QVVSKHSGTL

250 260 270 280 290 300
VLYRGRNYDP KKRPKIPLML WKPHEPVYPR LIKTTIDGLS IDETKAMRKK GLAVPALTKL

310 320 330 340 350 360
AKNGYYGSLV PMVRDAFLVS ELVRIDCLGL ERKDYKKIGA KLRDLVPCIL VTFDKEQVVI

370 380 390 400
WRGKDYKPPK EDDEYSSFIH RESSIDSDVD LSCSRGAQDS PDETT


References and documentation are available.

Number of amino acids: 405 Molecular weight: 46393.16 Theoretical pI: 9.43
Amino acid composition: 
Ala (A) 14 3.5% Arg (R) 32 7.9% Asn (N) 17 4.2% Asp (D) 29 7.2% Cys (C) 7 1.7% Gln (Q) 10 2.5% Glu (E) 24 5.9% Gly (G) 20 4.9% His (H) 10 2.5% Ile (I) 15 3.7% Leu (L) 40 9.9% Lys (K) 38 9.4% Met (M) 6 1.5% Phe (F) 14 3.5% Pro (P) 30 7.4% Ser (S) 33 8.1% Thr (T) 19 4.7% Trp (W) 4 1.0% Tyr (Y) 13 3.2% Val (V) 30 7.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 53 Total number of positively charged residues (Arg + Lys): 70 Atomic composition: Carbon C 2059 Hydrogen H 3292 Nitrogen N 590 Oxygen O 604 Sulfur S 13 Formula: C2059H3292N590O604S13 Total number of atoms: 6558 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 41745 Abs 0.1% (=1 g/l) 0.900, assuming all pairs of Cys residues form cystines Ext. coefficient 41370 Abs 0.1% (=1 g/l) 0.892, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 41.77 This classifies the protein as unstable. Aliphatic index: 77.90 Grand average of hydropathicity (GRAVY): -0.695