ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MFQNVRIVLV NPSHPGNIGA AARAMKTMGF SRLYLVKPEL FPHEQATARA AGADAVLASA 

        70         80         90        100        110        120 
RVVDDLTAAL EGCNLVFGTS ARSRTLPWPL KTPRECAEQS VQHQGNIAIV FGRERSGLTN 

       130        140        150        160        170        180 
EELAQCQYHV TIPTEAAFSS LNLAQAVQIL TYEIRMAKLN AVDPRHQNTP IQQLATADQM 

       190        200        210        220        230        240 
EGFYVHLEKT LVDIKFIDPK QPKMLMKRLR RLFNRAQIDE TELNILRGIL ASIHRRDDCC 

References and documentation are available.

Number of amino acids: 240

Molecular weight: 26801.92

Theoretical pI: 8.87

Amino acid composition: 
Ala (A)  28	 11.7%
Arg (R)  19	  7.9%
Asn (N)  11	  4.6%
Asp (D)  10	  4.2%
Cys (C)   5	  2.1%
Gln (Q)  15	  6.2%
Glu (E)  14	  5.8%
Gly (G)  11	  4.6%
His (H)   7	  2.9%
Ile (I)  14	  5.8%
Leu (L)  25	 10.4%
Lys (K)   9	  3.8%
Met (M)   7	  2.9%
Phe (F)   9	  3.8%
Pro (P)  12	  5.0%
Ser (S)  10	  4.2%
Thr (T)  14	  5.8%
Trp (W)   1	  0.4%
Tyr (Y)   4	  1.7%
Val (V)  15	  6.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 24
Total number of positively charged residues (Arg + Lys): 28

Atomic composition:

Carbon      C	      1178
Hydrogen    H	      1905
Nitrogen    N	       347
Oxygen      O	       343
Sulfur      S	        12

Formula: C1178H1905N347O343S12
Total number of atoms: 3785

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    11710
Abs 0.1% (=1 g/l)   0.437, assuming all pairs of Cys residues form cystines


Ext. coefficient    11460
Abs 0.1% (=1 g/l)   0.428, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 40.52
This classifies the protein as unstable.



Aliphatic index: 93.17

Grand average of hydropathicity (GRAVY): -0.180