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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MFRDRTNLFL SYRRTFPHNI TFSSGKAPLG DDQDIEMGTY PMMNMSHDIS ARLTDERKNK

70 80 90 100 110 120
HENHSDALPP IFIDIAQDVD DYLLEVRRLS EQLAKVYRKN SLPGFEDKSH DEALIEDLSF

130 140 150 160 170 180
KVIQMLQKCY AVMKRLKTIY NSQFVDGKQL SREELIILDN LQKIYAEKIQ TESNKFRVLQ

190 200 210 220 230 240
NNYLKFLNKD DLKPIRNKAS AENTLLLDDE EEEAAREKRE GLDIEDYSKR TLQRQQQLHD

250 260 270 280 290 300
TSAEAYLRER DEEITQLARG VLEVSTIFRE MQDLVVDQGT IVDRIDYNLE NTVVELKSAD

310 320 330 340 350 360
KELNKATHYQ KRTQKCKVIL LLTLCVIALF FFVMLKPHGG GSGGRNNGSN KYNNDDNKTV

370 380 390
NNSHDDGSNT HINDEESNLP SIVEVTESEN DALDDLL


References and documentation are available.

Number of amino acids: 397 Molecular weight: 45875.46 Theoretical pI: 5.10
Amino acid composition: 
Ala (A) 19 4.8% Arg (R) 24 6.0% Asn (N) 29 7.3% Asp (D) 37 9.3% Cys (C) 3 0.8% Gln (Q) 19 4.8% Glu (E) 34 8.6% Gly (G) 15 3.8% His (H) 10 2.5% Ile (I) 23 5.8% Leu (L) 45 11.3% Lys (K) 29 7.3% Met (M) 9 2.3% Phe (F) 14 3.5% Pro (P) 9 2.3% Ser (S) 25 6.3% Thr (T) 20 5.0% Trp (W) 0 0.0% Tyr (Y) 13 3.3% Val (V) 20 5.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 71 Total number of positively charged residues (Arg + Lys): 53 Atomic composition: Carbon C 1999 Hydrogen H 3192 Nitrogen N 566 Oxygen O 646 Sulfur S 12 Formula: C1999H3192N566O646S12 Total number of atoms: 6415 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 19495 Abs 0.1% (=1 g/l) 0.425, assuming all pairs of Cys residues form cystines Ext. coefficient 19370 Abs 0.1% (=1 g/l) 0.422, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 44.76 This classifies the protein as unstable. Aliphatic index: 86.20 Grand average of hydropathicity (GRAVY): -0.716