ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MFRLRAHGKK PITITTTTTT TASTFLYWSP ESSPTALSSP TNLDPNIWSN LPNHLLEHIL 

        70         80         90        100        110        120 
SLLPFKTLLT LRSISRHLRS LILSPSFISD HSFSLPSFLL LSHPQSFNSF PLFNPNLISW 

       130        140        150        160        170        180 
CTLPLPRSLS LTCASSLLSS SNGLLCFSLS PSSVSSLSIF NPLTRSSRSI KLPCYPFPFE 

       190        200        210        220        230        240 
LLSLVTSPKG YKIFTLCSSS SAASSRSVCL YDSGDRSWRK FGGVDQVLPR GFNQDGVFYN 

       250        260        270        280        290        300 
GSLYFARSEP FLIVSVDLND GKWTTATGDG VFPADDEITF ARLVSDPEKK ILYMVGGIGS 

       310        320        330        340        350        360 
NGICRSIKIW EFKEETESWI EVETLPDIVC RKFTSVCYHN YEHVYCLWHK EMICVCCYNW 

       370        380        390        400 
PEILFFHVGR RTWHWVPKCP SLPEKWSCGF RWFSFVPSLS ASV 

References and documentation are available.

Number of amino acids: 403

Molecular weight: 45447.27

Theoretical pI: 8.57

Amino acid composition: 
Ala (A)  11	  2.7%
Arg (R)  19	  4.7%
Asn (N)  15	  3.7%
Asp (D)  13	  3.2%
Cys (C)  15	  3.7%
Gln (Q)   3	  0.7%
Glu (E)  16	  4.0%
Gly (G)  18	  4.5%
His (H)  11	  2.7%
Ile (I)  22	  5.5%
Leu (L)  50	 12.4%
Lys (K)  16	  4.0%
Met (M)   3	  0.7%
Phe (F)  28	  6.9%
Pro (P)  30	  7.4%
Ser (S)  63	 15.6%
Thr (T)  26	  6.5%
Trp (W)  13	  3.2%
Tyr (Y)  11	  2.7%
Val (V)  20	  5.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 29
Total number of positively charged residues (Arg + Lys): 35

Atomic composition:

Carbon      C	      2081
Hydrogen    H	      3161
Nitrogen    N	       529
Oxygen      O	       580
Sulfur      S	        18

Formula: C2081H3161N529O580S18
Total number of atoms: 6369

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    88765
Abs 0.1% (=1 g/l)   1.953, assuming all pairs of Cys residues form cystines


Ext. coefficient    87890
Abs 0.1% (=1 g/l)   1.934, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 61.77
This classifies the protein as unstable.



Aliphatic index: 86.80

Grand average of hydropathicity (GRAVY): 0.042