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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MFSAPPATIN GADNYISPDP LTAREFGEAE METILDGDDT ELPEITLPGA PIPEGQVEEW

70 80 90 100 110 120
QKSRNMGFVM DPVIARGIAW FDAKPGQDGH ATKEDRTLYP TTTRVGDEWS DNYKGFVAEA

130 140 150 160 170 180
FATTLGPQAA EDLTQRFADF IESIKHYREE IRKDVDIVEA EPLDDAYSIA LCIYAVYFHN

190 200 210 220 230 240
GAAGQSGFFG SQSTYEVRQP LVEWVNVSEQ QPSVELGKEV MSQTPPVQHK DFWKYIYQLV

250 260 270 280 290 300
CRGMLKQASH CLHNSGAGEV DPSCQETLEQ TIDILSRYPQ GPGNVSFYFR QWHNSISTVQ

310 320 330 340 350 360
SKLLKINDAK IQKGLTTLLQ VLAGDEDAIM GTNHTWYDAL VTQQQYVDPC DSRMKGYYDA

370 380 390 400 410 420
AVANYPVDTF TVWEAGASHA IKGSLLLAIE TLENCDSVIA ALVSNMCYDA GLLNGYGAAN

430 440 450 460 470 480
PAALPDYHLT NLALQCIGYD NLINVGIEVL QKLRDVAPAR QILSLLLPRL PYDSAREIDW

490 500 510 520 530 540
AIKKCKQNGL VEVEAEILQT LAQKAIHNNN NLMGLCMFAK NGNIAALRYH CWKLFKNALV

550 560 570 580 590 600
AESPVEGDKS LADYVKDPAS VSDVPAEVAE CIAPYAVLTE YFNLRRSGQL VKSSEYLLAL

610 620 630 640 650 660
FEFPLLPTEY LGLLIHQLIN YVSPISQQFN FSTSQFMTLL SAFDKWDKSQ GTPAFEQGEE

670 680 690 700
LIKDMVDHSS DQNDWRKTFK IHELVMSELR LARTSVATMS SLKGLGGR


References and documentation are available.

Number of amino acids: 708 Molecular weight: 78777.06 Theoretical pI: 4.79
Amino acid composition: 
Ala (A) 66 9.3% Arg (R) 24 3.4% Asn (N) 31 4.4% Asp (D) 45 6.4% Cys (C) 12 1.7% Gln (Q) 38 5.4% Glu (E) 48 6.8% Gly (G) 44 6.2% His (H) 15 2.1% Ile (I) 38 5.4% Leu (L) 71 10.0% Lys (K) 33 4.7% Met (M) 15 2.1% Phe (F) 26 3.7% Pro (P) 35 4.9% Ser (S) 46 6.5% Thr (T) 36 5.1% Trp (W) 12 1.7% Tyr (Y) 29 4.1% Val (V) 44 6.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 93 Total number of positively charged residues (Arg + Lys): 57 Atomic composition: Carbon C 3521 Hydrogen H 5436 Nitrogen N 924 Oxygen O 1075 Sulfur S 27 Formula: C3521H5436N924O1075S27 Total number of atoms: 10983 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 109960 Abs 0.1% (=1 g/l) 1.396, assuming all pairs of Cys residues form cystines Ext. coefficient 109210 Abs 0.1% (=1 g/l) 1.386, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 42.79 This classifies the protein as unstable. Aliphatic index: 87.39 Grand average of hydropathicity (GRAVY): -0.226