ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MFSAQKPIYG NGAGVNMGGG GPSTNNPGSM SMPGVPTSMG PGMNQQIPSG GPMLMGNTPN 

        70         80         90        100        110        120 
NNNSNENGEN NGNNGNNGGN DANATRNNPN MVNNRGAVHA LDDPNVYHWI CQLTYGPQKE 

       130        140        150        160        170        180 
QALLELGRKR EQFDDLAVVL WSSFGVMTSL LNEIISVYPM LQPQMLSNNL SNRVCNALVL 

       190        200        210        220        230        240 
LQCVASHPET KHLFLQAHIP LFLFPFLNTT SRQRTFEYLR LTSLGVIGAL VKNDSQDVIT 

       250        260        270        280        290        300 
FLLRTDIVPL CLRIMESSSE LSKTVAIFIL QKILLDDVGL QYICATLERF YAVTNVLKDM 

       310        320        330        340        350        360 
VEHLTVSTPP GRLLKHIIRC YLRLSDDLEA RRLLKIVLPA KLRDNTFTEV LRDDVGSKRC 

       370 
LAQLLLTLNE ETS 

References and documentation are available.

Number of amino acids: 373

Molecular weight: 41155.27

Theoretical pI: 6.66

Amino acid composition: 
Ala (A)  18	  4.8%
Arg (R)  19	  5.1%
Asn (N)  36	  9.7%
Asp (D)  16	  4.3%
Cys (C)   7	  1.9%
Gln (Q)  16	  4.3%
Glu (E)  16	  4.3%
Gly (G)  28	  7.5%
His (H)   7	  1.9%
Ile (I)  17	  4.6%
Leu (L)  52	 13.9%
Lys (K)  12	  3.2%
Met (M)  14	  3.8%
Phe (F)  12	  3.2%
Pro (P)  21	  5.6%
Ser (S)  25	  6.7%
Thr (T)  22	  5.9%
Trp (W)   2	  0.5%
Tyr (Y)   8	  2.1%
Val (V)  25	  6.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 32
Total number of positively charged residues (Arg + Lys): 31

Atomic composition:

Carbon      C	      1806
Hydrogen    H	      2904
Nitrogen    N	       510
Oxygen      O	       545
Sulfur      S	        21

Formula: C1806H2904N510O545S21
Total number of atoms: 5786

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    23295
Abs 0.1% (=1 g/l)   0.566, assuming all pairs of Cys residues form cystines


Ext. coefficient    22920
Abs 0.1% (=1 g/l)   0.557, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 36.91
This classifies the protein as stable.



Aliphatic index: 96.41

Grand average of hydropathicity (GRAVY): -0.139