ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MFSRLSLFRR AALAPAPMRM SFRTIYQKTE DELPRRIVPK LATFYSANPN HEDRINRLER 

        70         80         90        100        110        120 
LLRKYIKLPS QNNNEAQQTK APWISFDEYA LIGGGTKLKP TQYTQLLYML NKLHNIDPQL 

       130        140        150        160        170        180 
TNDEITSELS QYYKKSSMLS NNIKIKTLDE FGRSIAVGKR KSSTAKVFVV RGTGEILVNG 

       190        200        210        220        230        240 
RQLNDYFLKM KDRESIMYPL QVIESVGKYN IFATTSGGGP TGQAESIMHA IAKALVVFNP 

       250        260        270 
LLKSRLHKAG VLTRDYRHVE RKKPGKKKAR KMPTWVKR 

References and documentation are available.

Number of amino acids: 278

Molecular weight: 31925.17

Theoretical pI: 10.25

Amino acid composition: 
Ala (A)  18	  6.5%
Arg (R)  22	  7.9%
Asn (N)  15	  5.4%
Asp (D)   9	  3.2%
Cys (C)   0	  0.0%
Gln (Q)  11	  4.0%
Glu (E)  14	  5.0%
Gly (G)  15	  5.4%
His (H)   5	  1.8%
Ile (I)  17	  6.1%
Leu (L)  28	 10.1%
Lys (K)  28	 10.1%
Met (M)   9	  3.2%
Phe (F)  10	  3.6%
Pro (P)  14	  5.0%
Ser (S)  19	  6.8%
Thr (T)  17	  6.1%
Trp (W)   2	  0.7%
Tyr (Y)  12	  4.3%
Val (V)  13	  4.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 23
Total number of positively charged residues (Arg + Lys): 50

Atomic composition:

Carbon      C	      1430
Hydrogen    H	      2316
Nitrogen    N	       410
Oxygen      O	       399
Sulfur      S	         9

Formula: C1430H2316N410O399S9
Total number of atoms: 4564

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    28880
Abs 0.1% (=1 g/l)   0.905

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 49.92
This classifies the protein as unstable.



Aliphatic index: 83.17

Grand average of hydropathicity (GRAVY): -0.553