ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGCVSSNLLN HDEDFSQIGG GSSAFGHHIV KLTSTTYGLL TLDPPPPPSP PMTPPEKFTV 

        70         80         90        100        110        120 
DTKSKSIWSE PRVIKSEPEI INSWELMSGL DGESFRFTPL PKTPVKYKVF GGENKENSDP 

       130        140        150        160        170        180 
SRRNPRKNLN DEVLKPLDLN REDSDSNSRS PRKSFKPLDL KLDEKFERIC PPGGENRVVM 

       190        200        210        220        230        240 
YTTSLRGVRQ TFEACNAVRA AVESFGVVVC ERDVSMDRRF REELVSLMAK RVGDEGVAAL 

       250        260        270        280        290        300 
PPRVFVKGRY IGGGEEVLRL VEEGSFGELI SGIPRKKAGG CESGACDGCG GLFFLPCFRC 

       310        320        330 
NGSCKMVKGW GSASVVVRCN ECNENGLVPC PICS 

References and documentation are available.

Number of amino acids: 334

Molecular weight: 36585.73

Theoretical pI: 7.42

Amino acid composition: 
Ala (A)  11	  3.3%
Arg (R)  24	  7.2%
Asn (N)  16	  4.8%
Asp (D)  16	  4.8%
Cys (C)  14	  4.2%
Gln (Q)   2	  0.6%
Glu (E)  28	  8.4%
Gly (G)  33	  9.9%
His (H)   3	  0.9%
Ile (I)  11	  3.3%
Leu (L)  26	  7.8%
Lys (K)  21	  6.3%
Met (M)   7	  2.1%
Phe (F)  16	  4.8%
Pro (P)  27	  8.1%
Ser (S)  32	  9.6%
Thr (T)  12	  3.6%
Trp (W)   3	  0.9%
Tyr (Y)   4	  1.2%
Val (V)  28	  8.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 44
Total number of positively charged residues (Arg + Lys): 45

Atomic composition:

Carbon      C	      1596
Hydrogen    H	      2540
Nitrogen    N	       454
Oxygen      O	       489
Sulfur      S	        21

Formula: C1596H2540N454O489S21
Total number of atoms: 5100

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    23335
Abs 0.1% (=1 g/l)   0.638, assuming all pairs of Cys residues form cystines


Ext. coefficient    22460
Abs 0.1% (=1 g/l)   0.614, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 47.32
This classifies the protein as unstable.



Aliphatic index: 70.81

Grand average of hydropathicity (GRAVY): -0.407