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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGDEKLSRHT SLKRARSLSE SIKGLFKPSG ISGSNNAAAP SSRPGQDQAH SHQTARIITS

70 80 90 100 110 120
NVSSPSISPV HSPVLQAAPK HHKLGVPNIA KLSLSPSREP SLNSENEMFS QESFISEKDE

130 140 150 160 170 180
DEANLLERED LQNKKEEKAR AKHVRSKEAY VPHHRYTVGS DEVERQPRER LKNFPQNAGS

190 200 210 220 230 240
SNPANSNANH VLDQENNFSI DAMLDYDEES KLRRRNSLGV RNHSNRTRSR KNSLSTPRSP

250 260 270 280 290 300
PMKNGNGGMN SNATNNVGNG TGNRIYMRGR NHSDSISASS LPKFQEIECK CILDLGHFKV

310 320 330 340 350 360
FENGYHEHSL RVLPIITNNK NVDSGDEKDA DASVNSGDDG DNDSEANMHK QKSVFSLSGL

370 380 390 400 410 420
FKSHKDGNQQ QQQQQQQEEN GEQINLEKAF SIIPSQRFIK SQTLKKSRTS NLKNGNNDEL

430 440 450 460 470 480
MKNDGKNIPQ IVNPNAAVGV EELKLINALS EKIRKGLKSE NTKGNNGEGR SNSNKQEDSD

490 500 510 520 530 540
DTEGKAGTTN DDTSHKPCSQ KYGKSIGVVG AGAYGVVKIC ARCKTAKDVL PYSTYSNGKK

550 560 570 580 590 600
LFFAVKELKP KPGDQIDKFC TRLTSEFIIG HSLSHPHFEA NAMIAGNVSR TTPPKHVFNA

610 620 630 640 650 660
PNILKILDLM EYSNSFVEVM EFCASGDLYS LLTRNNISNE SNNGSSRLIQ TVKEGSGSPL

670 680 690 700 710 720
HPLEADCFMK QLLNGVQYMH DHGIAHCDLK PENILFQPNG LLKICDFGTS SVFQTAWEKH

730 740 750 760 770 780
VHFQSGAMGS EPYVAPEEFI RDAEYDPRLV DCWSCGIVYC TMVMGQYLWK IAIPEKDSLF

790 800 810 820 830 840
KSFLSEIKDD GQFYLFEELR HVSSELNRLR KIALYRTFQV DPTKRITIEQ LLQSSWMRKT

850
KCCVVYRHLH TKVSK


References and documentation are available.

Number of amino acids: 855 Molecular weight: 95454.86 Theoretical pI: 8.63
Amino acid composition: 
Ala (A) 45 5.3% Arg (R) 43 5.0% Asn (N) 69 8.1% Asp (D) 44 5.1% Cys (C) 15 1.8% Gln (Q) 38 4.4% Glu (E) 59 6.9% Gly (G) 55 6.4% His (H) 31 3.6% Ile (I) 43 5.0% Leu (L) 65 7.6% Lys (K) 69 8.1% Met (M) 17 2.0% Phe (F) 31 3.6% Pro (P) 39 4.6% Ser (S) 95 11.1% Thr (T) 32 3.7% Trp (W) 4 0.5% Tyr (Y) 19 2.2% Val (V) 42 4.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 103 Total number of positively charged residues (Arg + Lys): 112 Atomic composition: Carbon C 4130 Hydrogen H 6560 Nitrogen N 1226 Oxygen O 1315 Sulfur S 32 Formula: C4130H6560N1226O1315S32 Total number of atoms: 13263 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 51185 Abs 0.1% (=1 g/l) 0.536, assuming all pairs of Cys residues form cystines Ext. coefficient 50310 Abs 0.1% (=1 g/l) 0.527, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 44.21 This classifies the protein as unstable. Aliphatic index: 68.77 Grand average of hydropathicity (GRAVY): -0.764