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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGFNIAMLCD FFYPQLGGVE FHIYHLSQKL IDLGHSVVII THAYKDRVGV RHLTNGLKVY

70 80 90 100 110 120
HVPFFVIFRE TTFPTVFSTF PIIRNILLRE QIQIVHSHGS ASTFAHEGIL HANTMGLRTV

130 140 150 160 170 180
FTDHSLYGFN NLTSIWVNKL LTFTLTNIDR VICVSNTCKE NMIVRTELSP DIISVIPNAV

190 200 210 220 230 240
VSEDFKPRDP TGGTKRKQSR DKIVIVVIGR LFPNKGSDLL TRIIPKVCSS HEDVEFIVAG

250 260 270 280 290 300
DGPKFIDFQQ MIESHRLQKR VQLLGSVPHE KVRDVLCQGD IYLHASLTEA FGTILVEAAS

310 320 330 340 350 360
CNLLIVTTQV GGIPEVLPNE MTVYAEQTSV SDLVQATNKA INIIRSKALD TSSFHDSVSK

370 380 390 400 410 420
MYDWMDVAKR TVEIYTNISS TSSADDKDWM KMVANLYKRD GIWAKHLYLL CGIVEYMLFF

430 440 450
LLEWLYPRDE IDLAPKWPKK TVSNETKEAR ET


References and documentation are available.

Number of amino acids: 452 Molecular weight: 51242.22 Theoretical pI: 6.79
Amino acid composition: 
Ala (A) 21 4.6% Arg (R) 21 4.6% Asn (N) 19 4.2% Asp (D) 26 5.8% Cys (C) 7 1.5% Gln (Q) 13 2.9% Glu (E) 23 5.1% Gly (G) 23 5.1% His (H) 17 3.8% Ile (I) 39 8.6% Leu (L) 41 9.1% Lys (K) 26 5.8% Met (M) 11 2.4% Phe (F) 23 5.1% Pro (P) 17 3.8% Ser (S) 32 7.1% Thr (T) 33 7.3% Trp (W) 6 1.3% Tyr (Y) 13 2.9% Val (V) 41 9.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 49 Total number of positively charged residues (Arg + Lys): 47 Atomic composition: Carbon C 2317 Hydrogen H 3645 Nitrogen N 613 Oxygen O 661 Sulfur S 18 Formula: C2317H3645N613O661S18 Total number of atoms: 7254 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 52745 Abs 0.1% (=1 g/l) 1.029, assuming all pairs of Cys residues form cystines Ext. coefficient 52370 Abs 0.1% (=1 g/l) 1.022, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 37.93 This classifies the protein as stable. Aliphatic index: 99.98 Grand average of hydropathicity (GRAVY): 0.006