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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGGELVTGLG ALRRRKRLLE QEKRVAGWAL VLAGTGIGLM VLHAEMLWFL GCKWVLYLLL

70 80 90 100 110 120
VKCLITLSTA FLLCLIVVFH AKEVQLFMTD NGLRDWRVAL TRRQVAQILL ELLVCGVHPV

130 140 150 160 170 180
PLRSPHCTLA GEATDSQAWP GFLGEGEALL SLAMLLRLYL VPRAVLLRSG VLLNASYRSI

190 200 210 220 230 240
GALNQVRFRH WFVAKLYMNT HPGRLLLGLT LGLWLTTAWV LSVAERQAVN ATGHLTDTLW

250 260 270 280 290 300
LIPITFLTIG YGDVVPGTLW GKIVCLCTGV MGVCCTALLV AVVARKLEFN KAEKHVHNFM

310 320 330 340 350 360
MDIHYAKEMK ESAARLLQEA WMYYKHTRRK DSRAARRHQR KMLAAIHTFR QVRLKHRKLR

370 380 390 400 410 420
EQVNSMVDIS KMHMILCDLQ LGLSASHLAL EKRIDGLAGK LDALTELLST ALQQQPPEPI


QEAT


References and documentation are available.

Number of amino acids: 424 Molecular weight: 47638.71 Theoretical pI: 9.76
Amino acid composition: 
Ala (A) 40 9.4% Arg (R) 31 7.3% Asn (N) 8 1.9% Asp (D) 11 2.6% Cys (C) 10 2.4% Gln (Q) 16 3.8% Glu (E) 20 4.7% Gly (G) 30 7.1% His (H) 16 3.8% Ile (I) 15 3.5% Leu (L) 77 18.2% Lys (K) 20 4.7% Met (M) 15 3.5% Phe (F) 11 2.6% Pro (P) 11 2.6% Ser (S) 15 3.5% Thr (T) 25 5.9% Trp (W) 11 2.6% Tyr (Y) 8 1.9% Val (V) 34 8.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 31 Total number of positively charged residues (Arg + Lys): 51 Atomic composition: Carbon C 2157 Hydrogen H 3498 Nitrogen N 604 Oxygen O 559 Sulfur S 25 Formula: C2157H3498N604O559S25 Total number of atoms: 6843 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 73045 Abs 0.1% (=1 g/l) 1.533, assuming all pairs of Cys residues form cystines Ext. coefficient 72420 Abs 0.1% (=1 g/l) 1.520, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 47.59 This classifies the protein as unstable. Aliphatic index: 117.31 Grand average of hydropathicity (GRAVY): 0.280