ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGGQMQQNNA AAATALYDGA LPTNDAGDAV MARWLQSAGL QHLASPVAST GNDQRHLPNL 

        70         80         90        100        110        120 
LMQGYGAQTA EEKQRLFQLM RNLNFNGEST SESYTPTAHT SAAMPSSEGF FSPEFRGDFG 

       130        140        150        160        170        180 
AGLLDLHAMD DTELLSEHVI TEPFEPSPFM PSVNKEFEED YNLAANRQQR QQTEAEPLGL 

       190        200        210        220        230        240 
LPKSDKENNS VAKIKVVVRK RPLNKKETAK KEEDVVTVSD NSLTVHEPRV KVDLTAYVEK 

       250        260        270        280        290        300 
HEFCFDAVLD EDVSNDEVYR ATIEPIIPII FQRTKATCFA YGQTGSGKTF TMKPLPIRAV 

       310        320        330        340        350        360 
EDLMRLLRQP VYSNQRFKLW LSYFEIYGGK LFDLLSERKK LCMREDGRQQ VCIVGLQEYE 

       370        380        390        400        410        420 
VSDVQIVKDF IEKGNAERST GSTGANEESS RSHAILQLVV KKHVEVKDTR RRNNDSNELP 

       430        440        450        460        470        480 
GKVVGKISFI DLAGSERGAD TTDNDRQTRI EGAEINKSLL ALKECIRALD NDQLHIPFRG 

       490        500        510        520        530        540 
SKLTEVLRDS FVGNSRTVMI SCISPNAGSC EHTLNTLRYA DRVKSLSKSG NSKKDQTANS 

       550        560        570        580        590        600 
MPPVNKDPLL GPNDVEDVFE PPQEVNVPET RRRVVEKDSN SSTSGIDFRQ PTNYREESGI 

       610        620        630        640        650        660 
PSFSMDKGRS EPNSSFAGST SQRNNISSYP QETSDREEKV KKVSPPRGKG LREEKPDRPQ 

       670        680        690        700        710        720 
NWSKRDVSSS DIPTLTNFRQ NASETASRQY ETASRQYETD PSLDENLDAL LEEEEALIAA 

       730        740        750        760        770        780 
HRKEIEDTME IVREEMKLLA EVDQPGSMIE NYVTQLSFVL SRKAAGLVSL QARLARFQHR 

       790 
LKEQEILSRK RVPR 

References and documentation are available.

Number of amino acids: 794

Molecular weight: 89081.66

Theoretical pI: 5.56

Amino acid composition: 
Ala (A)  54	  6.8%
Arg (R)  57	  7.2%
Asn (N)  43	  5.4%
Asp (D)  48	  6.0%
Cys (C)   7	  0.9%
Gln (Q)  39	  4.9%
Glu (E)  73	  9.2%
Gly (G)  42	  5.3%
His (H)  13	  1.6%
Ile (I)  30	  3.8%
Leu (L)  67	  8.4%
Lys (K)  48	  6.0%
Met (M)  17	  2.1%
Phe (F)  28	  3.5%
Pro (P)  41	  5.2%
Ser (S)  72	  9.1%
Thr (T)  44	  5.5%
Trp (W)   3	  0.4%
Tyr (Y)  17	  2.1%
Val (V)  51	  6.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 121
Total number of positively charged residues (Arg + Lys): 105

Atomic composition:

Carbon      C	      3856
Hydrogen    H	      6174
Nitrogen    N	      1124
Oxygen      O	      1252
Sulfur      S	        24

Formula: C3856H6174N1124O1252S24
Total number of atoms: 12430

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    42205
Abs 0.1% (=1 g/l)   0.474, assuming all pairs of Cys residues form cystines


Ext. coefficient    41830
Abs 0.1% (=1 g/l)   0.470, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 50.51
This classifies the protein as unstable.



Aliphatic index: 73.07

Grand average of hydropathicity (GRAVY): -0.708