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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGGSSDSDSH DGYLTSEYNS SNSLFSLNTG NSYSSASLDR ATLDCQDSVF FDNHKSSLLS

70 80 90 100 110 120
TEVPRFISND PLHLPITLNY KRDNADPTYT NGKVNKFMIV LIGLPATGKS TISSHLIQCL

130 140 150 160 170 180
KNNPLTNSLR CKVFNAGKIR RQISCATISK PLLLSNTSSE DLFNPKNNDK KETYARITLQ

190 200 210 220 230 240
KLFHEINNDE CDVGIFDATN STIERRRFIF EEVCSFNTDE LSSFNLVPII LQVSCFNRSF

250 260 270 280 290 300
IKYNIHNKSF NEDYLDKPYE LAIKDFAKRL KHYYSQFTPF SLDEFNQIHR YISQHEEIDT

310 320 330 340 350 360
SLFFFNVINA GVVEPHSLNQ SHYPSTCGKQ IRDTIMVIEN FINHYSQMFG FEYIEAVKLF

370 380 390
FESFGNSSEE TLTTLDSVVN DKFFDDLQSL IESNGFA


References and documentation are available.

Number of amino acids: 397 Molecular weight: 45317.63 Theoretical pI: 5.39
Amino acid composition: 
Ala (A) 13 3.3% Arg (R) 14 3.5% Asn (N) 36 9.1% Asp (D) 26 6.5% Cys (C) 8 2.0% Gln (Q) 12 3.0% Glu (E) 23 5.8% Gly (G) 14 3.5% His (H) 12 3.0% Ile (I) 29 7.3% Leu (L) 36 9.1% Lys (K) 22 5.5% Met (M) 4 1.0% Phe (F) 32 8.1% Pro (P) 13 3.3% Ser (S) 48 12.1% Thr (T) 24 6.0% Trp (W) 0 0.0% Tyr (Y) 15 3.8% Val (V) 16 4.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 49 Total number of positively charged residues (Arg + Lys): 36 Atomic composition: Carbon C 2020 Hydrogen H 3085 Nitrogen N 533 Oxygen O 631 Sulfur S 12 Formula: C2020H3085N533O631S12 Total number of atoms: 6281 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 22850 Abs 0.1% (=1 g/l) 0.504, assuming all pairs of Cys residues form cystines Ext. coefficient 22350 Abs 0.1% (=1 g/l) 0.493, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 48.87 This classifies the protein as unstable. Aliphatic index: 78.82 Grand average of hydropathicity (GRAVY): -0.385