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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGGVFSGDRV FNDSKAIHNV DKQMLHNHDP TLSVSTPEVT TEMHERLNFP KVELHLHLDG

70 80 90 100 110 120
AVRFDTLIDL SQQKGIPLAG AKTVEELKKV LVTHEPANLS KVLEAFEIFL PVIRGDLAAI

130 140 150 160 170 180
ERVAYELCED QHNNGVVYFE GRYSPHLLLC NDYPEVTAAH VVAAVKKGFD RGEKQFGIKA

190 200 210 220 230 240
RSILCCIRGL DKKFPQLILD LATDLKQLGV VAIDVAGSAH GADEQYEPEV VAAFQEAHKR

250 260 270 280 290 300
GIHRTVHAGE SGGPKEVIKA IEDMYAERIG HGYRVMRDEE MYLEHFVNSK NVHLEACPYS

310 320 330 340 350 360
SVMTGAVPLD WKNHPIARWA KDDVNFSVSR DDPTCFDNSM LSELTLVHKQ IGLDVHQLWK

370 380 390
AQLNAARSCF LPEDEKAELV KRVEAGEPPR P


References and documentation are available.

Number of amino acids: 391 Molecular weight: 43675.76 Theoretical pI: 5.73
Amino acid composition: 
Ala (A) 34 8.7% Arg (R) 19 4.9% Asn (N) 14 3.6% Asp (D) 26 6.6% Cys (C) 7 1.8% Gln (Q) 12 3.1% Glu (E) 33 8.4% Gly (G) 25 6.4% His (H) 20 5.1% Ile (I) 17 4.3% Leu (L) 37 9.5% Lys (K) 25 6.4% Met (M) 8 2.0% Phe (F) 15 3.8% Pro (P) 19 4.9% Ser (S) 18 4.6% Thr (T) 13 3.3% Trp (W) 3 0.8% Tyr (Y) 9 2.3% Val (V) 37 9.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 59 Total number of positively charged residues (Arg + Lys): 44 Atomic composition: Carbon C 1941 Hydrogen H 3050 Nitrogen N 542 Oxygen O 576 Sulfur S 15 Formula: C1941H3050N542O576S15 Total number of atoms: 6124 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 30285 Abs 0.1% (=1 g/l) 0.693, assuming all pairs of Cys residues form cystines Ext. coefficient 29910 Abs 0.1% (=1 g/l) 0.685, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 37.44 This classifies the protein as stable. Aliphatic index: 90.00 Grand average of hydropathicity (GRAVY): -0.293