ProtParam
User-provided sequence:
10 20 30 40 50 60
MGIDHTSKQH KRSGHRTAPK SDNVYLKLLV KLYTFLARRT DAPFNKVVLK ALFLSKINRP
70 80 90 100 110 120
PVSVSRIARA LKQEGAANKT VVVVGTVTDD ARIFEFPKTT VAALRFTAGA RAKIVKAGGE
130 140 150 160 170 180
CITLDQLAVR APKGQNTLIL RGPRNSREAV RHFGMGPHKG KAPRILSTGR KFERARGRRR
SKGFKV
References and
documentation are available.
Number of amino acids: 186
Molecular weight: 20563.14
Theoretical pI: 11.71
Total number of negatively charged residues (Asp + Glu): 11
Total number of positively charged residues (Arg + Lys): 41
Atomic composition:
Carbon C 913
Hydrogen H 1525
Nitrogen N 291
Oxygen O 243
Sulfur S 3
Formula: C
913H
1525N
291O
243S
3
Total number of atoms: 2975
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 2980
Abs 0.1% (=1 g/l) 0.145, assuming all pairs of Cys residues form cystines
Ext. coefficient 2980
Abs 0.1% (=1 g/l) 0.145, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 40.14
This classifies the protein as unstable.
Aliphatic index: 83.92
Grand average of hydropathicity (GRAVY): -0.399