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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGIDHTSKQH KRSGHRTAPK SDNVYLKLLV KLYTFLARRT DAPFNKVVLK ALFLSKINRP

70 80 90 100 110 120
PVSVSRIARA LKQEGAANKT VVVVGTVTDD ARIFEFPKTT VAALRFTAGA RAKIVKAGGE

130 140 150 160 170 180
CITLDQLAVR APKGQNTLIL RGPRNSREAV RHFGMGPHKG KAPRILSTGR KFERARGRRR


SKGFKV


References and documentation are available.

Number of amino acids: 186 Molecular weight: 20563.14 Theoretical pI: 11.71
Amino acid composition: 
Ala (A) 20 10.8% Arg (R) 22 11.8% Asn (N) 6 3.2% Asp (D) 6 3.2% Cys (C) 1 0.5% Gln (Q) 4 2.2% Glu (E) 5 2.7% Gly (G) 15 8.1% His (H) 5 2.7% Ile (I) 8 4.3% Leu (L) 15 8.1% Lys (K) 19 10.2% Met (M) 2 1.1% Phe (F) 9 4.8% Pro (P) 9 4.8% Ser (S) 9 4.8% Thr (T) 13 7.0% Trp (W) 0 0.0% Tyr (Y) 2 1.1% Val (V) 16 8.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 11 Total number of positively charged residues (Arg + Lys): 41 Atomic composition: Carbon C 913 Hydrogen H 1525 Nitrogen N 291 Oxygen O 243 Sulfur S 3 Formula: C913H1525N291O243S3 Total number of atoms: 2975 Extinction coefficients: This protein does not contain any Trp residues. Experience shows that this could result in more than 10% error in the computed extinction coefficient. Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 2980 Abs 0.1% (=1 g/l) 0.145, assuming all pairs of Cys residues form cystines Ext. coefficient 2980 Abs 0.1% (=1 g/l) 0.145, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 40.14 This classifies the protein as unstable. Aliphatic index: 83.92 Grand average of hydropathicity (GRAVY): -0.399