ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGIIDKIKAI EEEMARTQKN KATEHHLGLL KGKLARYRQQ LLADEAGSGG GGGSGFEVAK 

        70         80         90        100        110        120 
SGDARVVLIG YPSVGKSSLL GKITTTKSEI AHYAFTTLTS VPGVLKYQGA EIQIVDLPGI 

       130        140        150        160        170        180 
IYGASQGKGR GRQVVATART ADLVLMVLDA TKSEHQRASL EKELENVGIR LNKEKPNIYY 

       190        200        210        220        230        240 
KKKETGGVKV TFTSPPKTNL TEQAIKMILR DYRIHNAEVL VRDDQCTIDD FIDVINEQHR 

       250        260        270        280        290        300 
NYVKCLYVYN KIDAVSLEEV DKLAREPNTV VMSCEMDLGL QDVVEEIWYQ LNLSRVYTKK 

       310        320        330        340        350        360 
RGVRPVFDDP LVVRNNSTIG DLCHGIHRDF KDKFKYALVW GSSAKHSPQK CGLNHRIDDE 


DVVSLFAK 

References and documentation are available.

Number of amino acids: 368

Molecular weight: 41006.00

Theoretical pI: 8.72

Amino acid composition: 
Ala (A)  24	  6.5%
Arg (R)  20	  5.4%
Asn (N)  14	  3.8%
Asp (D)  24	  6.5%
Cys (C)   5	  1.4%
Gln (Q)  14	  3.8%
Glu (E)  24	  6.5%
Gly (G)  30	  8.2%
His (H)  10	  2.7%
Ile (I)  24	  6.5%
Leu (L)  33	  9.0%
Lys (K)  33	  9.0%
Met (M)   6	  1.6%
Phe (F)   8	  2.2%
Pro (P)  10	  2.7%
Ser (S)  20	  5.4%
Thr (T)  20	  5.4%
Trp (W)   2	  0.5%
Tyr (Y)  14	  3.8%
Val (V)  33	  9.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 48
Total number of positively charged residues (Arg + Lys): 53

Atomic composition:

Carbon      C	      1814
Hydrogen    H	      2933
Nitrogen    N	       511
Oxygen      O	       547
Sulfur      S	        11

Formula: C1814H2933N511O547S11
Total number of atoms: 5816

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    32110
Abs 0.1% (=1 g/l)   0.783, assuming all pairs of Cys residues form cystines


Ext. coefficient    31860
Abs 0.1% (=1 g/l)   0.777, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.80
This classifies the protein as stable.



Aliphatic index: 92.93

Grand average of hydropathicity (GRAVY): -0.362