ProtParam
User-provided sequence:
10 20 30 40 50 60
MGIIEEKALF VTCGATVPFP KLVSCVLSDE FCQELIQYGF VRLIIQFGRN YSSEFEHLVQ
70 80 90 100 110 120
ERGGQRESQK IPIDQFGCGD TARQYVLMNG KLKVIGFDFS TKMQSIIRDY SDLVISHAGT
130 140 150 160 170 180
GSILDSLRLN KPLIVCVNDS LMDNHQQQIA DKFVELGYVW SCAPTETGLI AGLRASQTEK
190 200
LKPFPVSHNP SFERLLVETI YS
References and
documentation are available.
Number of amino acids: 202
Molecular weight: 22661.05
Theoretical pI: 5.58
Total number of negatively charged residues (Asp + Glu): 23
Total number of positively charged residues (Arg + Lys): 19
Atomic composition:
Carbon C 1015
Hydrogen H 1597
Nitrogen N 267
Oxygen O 300
Sulfur S 10
Formula: C
1015H
1597N
267O
300S
10
Total number of atoms: 3189
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 14815
Abs 0.1% (=1 g/l) 0.654, assuming all pairs of Cys residues form cystines
Ext. coefficient 14440
Abs 0.1% (=1 g/l) 0.637, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 34.11
This classifies the protein as stable.
Aliphatic index: 95.00
Grand average of hydropathicity (GRAVY): -0.025