ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGIRRLVSVI TRPIINKVNS SGQYSRVLAT REDQDKASPK YMNNDKIAKK PYTYRLFSIL 

        70         80         90        100        110        120 
GILSICSLLL ISLLKPFNGA DAPQCESIYM FPSYARIDGF DERYTPLAHK YHLYLYREQS 

       130        140        150        160        170        180 
VDREPLNGDE LQLDGIPVLF IPGNAGSFRQ CRSIASACSN IYFDSNTRAT LRNENVRNLD 

       190        200        210        220        230        240 
FFTADFNEDF TAFHGETMLD QAEYLNDAIK YILSLYERTP DYPHPKPQSV IIVGHSMGGI 

       250        260        270        280        290        300 
VSRVMLTLKN HVPGSISTIL TLSSPHAASP VTFDGDILKL YKNTNEYWRK QLSQNDSFFS 

       310        320        330        340        350        360 
KNISLVSITG GILDTTLPAD YASVEDLVSL ENGFTSFTTT IPDVWTPIDH LAIVWCKQLR 

       370        380        390        400        410        420 
EVLARLLLES IDASKPEKVK PLNQRLQIAR KLLLSGFEDY SWMNSKLNYP QENLQEFSDN 

       430        440        450        460        470        480 
FFSDYATLEM NDVLDFEMFN LEKWHNNYTK INIPSNISST EHLHFTLLTS LDMPMIYFCT 

       490        500        510        520        530        540 
ESRVNLSCIT AVDSILTVPR SSKDTQFAAD SSFGEAKNPF KAVSVGKNIL QKYDYLMISK 

       550        560        570        580        590        600 
PTYGEFSEQE GMEDNQGFLL ALLRNVSNVQ IVNTTPSQIL LFGEQLHLDG KDIEQVISFS 

       610        620        630        640        650        660 
NLWDSLLSYK LETKIEASNE GIASEETLFQ PFIRQWVYEP FESKWHLNII NKSLDINMHN 

       670        680        690        700        710        720 
VAPFIPLNES EPRSLQLSFF IPPGMSLEAK MTINWSLTLK MLFIRYRLAL ASFPVAFIAL 

       730        740        750        760        770        780 
VLSYQFYWYN KTSEFPSFDS TLGYILRKHG ILMFFTLFLA SPVVNNKLVQ RILYLLDPVG 

       790        800        810        820        830        840 
LNYPFLLSER NMHANFYYLG IRDWFMSTIG ILFGVMTVGL LALVSKIFGS LEILVIFLQR 

       850        860        870        880        890        900 
KLSKKNTEDK EAFDTIEHKA YGKGRLMASV LLLLLVFFHI PYQMAFVISL VIQIATCIRV 

       910        920        930        940        950        960 
ALLKLSNNEQ KLNLLNYNMT LLLLLLFVSA INIPIIIVFL HNVAIKWETS FRSHHNILAV 

       970        980        990       1000       1010       1020 
APIIFLVGNN SIFKMPNSVP LDTWDGKVTI ILFVYLTVFS FIYGIRNLYW IHHLVNIICA 


WLLFFETIH 

References and documentation are available.

Number of amino acids: 1029

Molecular weight: 117755.30

Theoretical pI: 6.27

Amino acid composition: 
Ala (A)  52	  5.1%
Arg (R)  38	  3.7%
Asn (N)  66	  6.4%
Asp (D)  47	  4.6%
Cys (C)   9	  0.9%
Gln (Q)  32	  3.1%
Glu (E)  51	  5.0%
Gly (G)  41	  4.0%
His (H)  24	  2.3%
Ile (I)  87	  8.5%
Leu (L) 135	 13.1%
Lys (K)  51	  5.0%
Met (M)  25	  2.4%
Phe (F)  67	  6.5%
Pro (P)  46	  4.5%
Ser (S)  90	  8.7%
Thr (T)  53	  5.2%
Trp (W)  15	  1.5%
Tyr (Y)  43	  4.2%
Val (V)  57	  5.5%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 98
Total number of positively charged residues (Arg + Lys): 89

Atomic composition:

Carbon      C	      5419
Hydrogen    H	      8373
Nitrogen    N	      1355
Oxygen      O	      1510
Sulfur      S	        34

Formula: C5419H8373N1355O1510S34
Total number of atoms: 16691

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   147070
Abs 0.1% (=1 g/l)   1.249, assuming all pairs of Cys residues form cystines


Ext. coefficient   146570
Abs 0.1% (=1 g/l)   1.245, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 42.87
This classifies the protein as unstable.



Aliphatic index: 105.26

Grand average of hydropathicity (GRAVY): 0.091