ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGKDNKEHKE SKESKTVDNY EARMPAVLPF AKPLASKKLN KKVLKTVKKA SKAKNVKRGV 

        70         80         90        100        110        120 
KEVVKALRKG EKGLVVIAGD ISPADVISHI PVLCEDHSVP YIFIPSKQDL GAAGATKRPT 

       130        140        150 
SVVFIVPGSN KKKDGKNKEE EYKESFNEVV KEVQAL 

References and documentation are available.

Number of amino acids: 156

Molecular weight: 17122.00

Theoretical pI: 9.73

Amino acid composition: 
Ala (A)  13	  8.3%
Arg (R)   4	  2.6%
Asn (N)   7	  4.5%
Asp (D)   7	  4.5%
Cys (C)   1	  0.6%
Gln (Q)   2	  1.3%
Glu (E)  13	  8.3%
Gly (G)   9	  5.8%
His (H)   3	  1.9%
Ile (I)   7	  4.5%
Leu (L)   9	  5.8%
Lys (K)  29	 18.6%
Met (M)   2	  1.3%
Phe (F)   4	  2.6%
Pro (P)   9	  5.8%
Ser (S)  11	  7.1%
Thr (T)   4	  2.6%
Trp (W)   0	  0.0%
Tyr (Y)   3	  1.9%
Val (V)  19	 12.2%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 20
Total number of positively charged residues (Arg + Lys): 33

Atomic composition:

Carbon      C	       765
Hydrogen    H	      1274
Nitrogen    N	       212
Oxygen      O	       224
Sulfur      S	         3

Formula: C765H1274N212O224S3
Total number of atoms: 2478

Extinction coefficients:

This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient     4470
Abs 0.1% (=1 g/l)   0.261, assuming all pairs of Cys residues form cystines


Ext. coefficient     4470
Abs 0.1% (=1 g/l)   0.261, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 43.65
This classifies the protein as unstable.



Aliphatic index: 83.65

Grand average of hydropathicity (GRAVY): -0.572