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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGKFSKIKKV QEEESAHQKM EWEAAGAKDS SSDDSSDESD NDDQPKQATE ETRKRAELWT

70 80 90 100 110 120
NRERVLVLCS RGADVRTRYL MKDIKDLLPH AKGDSKLDQQ KSLNVLNEIA EMKNCTKVMY

130 140 150 160 170 180
FESRKRKDTY LWMSNVEKGP SIKFLVHNVH TMKELKMSGN CLRASRPVLS FDDAFDKKPQ

190 200 210 220 230 240
LKLIKAVLMQ TLGTPHHHPR SQPFVDHVFN FSVGEGDKIW FRNFQIVDES LQLQEVGPRF

250 260 270 280 290 300
VLEMVRLFAG SFEGAVLYDN PNYVSPNVIR REHRKGQHSY IEKQLAVKAS NIKQAKVTEI

310 320 330 340 350
LAEKTVDLVG KEFDTQNNAA ADSEAAAQIT AQIEKRRVRK KKSQASKYTG SD


References and documentation are available.

Number of amino acids: 352 Molecular weight: 40233.70 Theoretical pI: 9.12
Amino acid composition: 
Ala (A) 26 7.4% Arg (R) 21 6.0% Asn (N) 16 4.5% Asp (D) 24 6.8% Cys (C) 3 0.9% Gln (Q) 19 5.4% Glu (E) 27 7.7% Gly (G) 15 4.3% His (H) 10 2.8% Ile (I) 13 3.7% Leu (L) 26 7.4% Lys (K) 38 10.8% Met (M) 10 2.8% Phe (F) 14 4.0% Pro (P) 11 3.1% Ser (S) 28 8.0% Thr (T) 14 4.0% Trp (W) 4 1.1% Tyr (Y) 7 2.0% Val (V) 26 7.4% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 51 Total number of positively charged residues (Arg + Lys): 59 Atomic composition: Carbon C 1763 Hydrogen H 2824 Nitrogen N 512 Oxygen O 539 Sulfur S 13 Formula: C1763H2824N512O539S13 Total number of atoms: 5651 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 32555 Abs 0.1% (=1 g/l) 0.809, assuming all pairs of Cys residues form cystines Ext. coefficient 32430 Abs 0.1% (=1 g/l) 0.806, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.23 This classifies the protein as unstable. Aliphatic index: 72.02 Grand average of hydropathicity (GRAVY): -0.753