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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGKLLQLALH PVEMKAALKL KFCRTPLFSI YDQSTSPYLL HCFELLNLTS RSFAAVIREL

70 80 90 100 110 120
HPELRNCVTL FYLILRALDT IEDDMSIEHD LKIDLLRHFH EKLLLTKWSF DGNAPDVKDR

130 140 150 160 170 180
AVLTDFESIL IEFHKLKPEY QEVIKEITEK MGNGMADYIL DENYNLNGLQ TVHDYDVYCH

190 200 210 220 230 240
YVAGLVGDGL TRLIVIAKFA NESLYSNEQL YESMGLFLQK TNIIRDYNED LVDGRSFWPK

250 260 270 280 290 300
EIWSQYAPQL KDFMKPENEQ LGLDCINHLV LNALSHVIDV LTYLAGIHEQ STFQFCAIPQ

310 320 330 340 350 360
VMAIATLALV FNNREVLHGN VKIRKGTTCY LILKSRTLRG CVEIFDYYLR DIKSKLAVQD

370 380 390 400 410 420
PNFLKLNIQI SKIEQFMEEM YQDKLPPNVK PNETPIFLKV KERSRYDDEL VPTQQEEEYK

430 440
FNMVLSIILS VLLGFYYIYT LHRA


References and documentation are available.

Number of amino acids: 444 Molecular weight: 51719.90 Theoretical pI: 5.58
Amino acid composition: 
Ala (A) 21 4.7% Arg (R) 18 4.1% Asn (N) 22 5.0% Asp (D) 27 6.1% Cys (C) 8 1.8% Gln (Q) 18 4.1% Glu (E) 33 7.4% Gly (G) 16 3.6% His (H) 14 3.2% Ile (I) 32 7.2% Leu (L) 64 14.4% Lys (K) 29 6.5% Met (M) 11 2.5% Phe (F) 22 5.0% Pro (P) 16 3.6% Ser (S) 21 4.7% Thr (T) 20 4.5% Trp (W) 3 0.7% Tyr (Y) 23 5.2% Val (V) 26 5.9% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 60 Total number of positively charged residues (Arg + Lys): 47 Atomic composition: Carbon C 2358 Hydrogen H 3680 Nitrogen N 598 Oxygen O 669 Sulfur S 19 Formula: C2358H3680N598O669S19 Total number of atoms: 7324 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 51270 Abs 0.1% (=1 g/l) 0.991, assuming all pairs of Cys residues form cystines Ext. coefficient 50770 Abs 0.1% (=1 g/l) 0.982, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 43.07 This classifies the protein as unstable. Aliphatic index: 106.04 Grand average of hydropathicity (GRAVY): -0.107