ProtParam
User-provided sequence:
10 20 30 40 50 60
MGKSAVIFVE RATPATLTEL KDALSNSILS VRDPWSIDFR TYRCSIKNLP ADVSKLMYSI
70 80 90 100 110 120
TFHHHGRQTV LIKDNSAMVT TAAAADIPPA LVFNGSSTGV PESIDTILSS KLSNIWMQRQ
130 140 150 160 170 180
LIKGDAGETL ILDGLTVRLV NLFSSTGFKG LLIELQADEA GEFETKIAGI EGHLAEIRAK
190 200 210
EYKTSSDSLG PDTSNEICDL AYQYVRALEL
References and
documentation are available.
Number of amino acids: 210
Molecular weight: 22894.11
Theoretical pI: 5.24
Total number of negatively charged residues (Asp + Glu): 26
Total number of positively charged residues (Arg + Lys): 20
Atomic composition:
Carbon C 1016
Hydrogen H 1632
Nitrogen N 270
Oxygen O 317
Sulfur S 6
Formula: C
1016H
1632N
270O
317S
6
Total number of atoms: 3241
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 18575
Abs 0.1% (=1 g/l) 0.811, assuming all pairs of Cys residues form cystines
Ext. coefficient 18450
Abs 0.1% (=1 g/l) 0.806, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 27.25
This classifies the protein as stable.
Aliphatic index: 100.38
Grand average of hydropathicity (GRAVY): -0.008