ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGLLNSSDKE IIKRALPKAS NKIIDVTVAR LYIAYPDKNE WQYTGLSGAL ALVDDLVGNT 

        70         80         90        100        110        120 
FFLKLVDING HRGVIWDQEL YVNFEYYQDR TFFHTFEMEE CFAGLLFVDI NEASHFLKRV 

       130        140        150        160        170        180 
QKRERYANRK TLLNKNAVAL TKKVREEQKS QVVHGPRGES LIDNQRKRYN YEDVDTIPTT 

       190        200        210        220        230        240 
KHKAPPPPPP TAETFDSDQT SSFSDINSTT ASAPTTPAPA LPPASPEVRK EETHPKHSLP 

       250        260        270        280        290        300 
PLPNQFAPLP DPPQHNSPPQ NNAPSQPQSN PFPFPIPEIP STQSATNPFP FPVPQQQFNQ 

       310        320        330        340        350        360 
APSMGIPQQN RPLPQLPNRN NRPVPPPPPM RTTTEGSGVR LPAPPPPPRR GPAPPPPPHR 

       370        380        390        400        410        420 
HVTSNTLNSA GGNSLLPQAT GRRGPAPPPP PRASRPTPNV TMQQNPQQYN NSNRPFGYQT 

       430        440        450        460        470        480 
NSNMSSPPPP PVTTFNTLTP QMTAATGQPA VPLPQNTQAP SQATNVPVAP PPPPASLGQS 

       490        500        510        520        530        540 
QIPQSAPSAP IPPTLPSTTS AAPPPPPAFL TQQPQSGGAP APPPPPQMPA TSTSGGGSFA 

       550        560        570        580        590        600 
ETTGDAGRDA LLASIRGAGG IGALRKVDKS QLDKPSVLLQ EARGESASPP AAAGNGGTPG 

       610        620        630 
GPPASLADAL AAALNKRKTK VGAHDDMDNG DDW 

References and documentation are available.

Number of amino acids: 633

Molecular weight: 67571.73

Theoretical pI: 9.25

Amino acid composition: 
Ala (A)  61	  9.6%
Arg (R)  31	  4.9%
Asn (N)  40	  6.3%
Asp (D)  26	  4.1%
Cys (C)   1	  0.2%
Gln (Q)  41	  6.5%
Glu (E)  22	  3.5%
Gly (G)  39	  6.2%
His (H)  11	  1.7%
Ile (I)  18	  2.8%
Leu (L)  42	  6.6%
Lys (K)  24	  3.8%
Met (M)   9	  1.4%
Phe (F)  21	  3.3%
Pro (P) 112	 17.7%
Ser (S)  47	  7.4%
Thr (T)  47	  7.4%
Trp (W)   3	  0.5%
Tyr (Y)  11	  1.7%
Val (V)  27	  4.3%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 48
Total number of positively charged residues (Arg + Lys): 55

Atomic composition:

Carbon      C	      2989
Hydrogen    H	      4668
Nitrogen    N	       856
Oxygen      O	       916
Sulfur      S	        10

Formula: C2989H4668N856O916S10
Total number of atoms: 9439

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    32890
Abs 0.1% (=1 g/l)   0.487, assuming all pairs of Cys residues form cystines


Ext. coefficient    32890
Abs 0.1% (=1 g/l)   0.487, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 64.46
This classifies the protein as unstable.



Aliphatic index: 58.97

Grand average of hydropathicity (GRAVY): -0.727