ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGNMIKKASL IALLPLFTAA AAAATDAETS MESGSSSHLK SFLMSVSMIG LSEIGDKTFL 

        70         80         90        100        110        120 
IAALMAMRHK RVLVFSAAAT SLAIMTILSG VVGHSAVAFL SERYTAFFAG ILFLVFGYKL 

       130        140        150        160        170        180 
TMEGLEMSKD AGVEEEMAEV EEEIAIKDMN QDMDDVEKGG DTAYDKQLKN ASIGKKIVHR 

       190        200        210        220        230        240 
IRELASFMFS PVWVQIFLMV FLGELGDRSQ ISIIAMATDS DYWYVIAGAV IGHAICSGLA 

       250        260        270        280 
VVGGKLLATR ISIRTITLAS SLLFFIFALM YIYQAFTTQD 

References and documentation are available.

Number of amino acids: 280

Molecular weight: 30340.54

Theoretical pI: 5.27

Amino acid composition: 
Ala (A)  36	 12.9%
Arg (R)   8	  2.9%
Asn (N)   3	  1.1%
Asp (D)  13	  4.6%
Cys (C)   1	  0.4%
Gln (Q)   6	  2.1%
Glu (E)  16	  5.7%
Gly (G)  20	  7.1%
His (H)   5	  1.8%
Ile (I)  25	  8.9%
Leu (L)  29	 10.4%
Lys (K)  14	  5.0%
Met (M)  17	  6.1%
Phe (F)  17	  6.1%
Pro (P)   2	  0.7%
Ser (S)  26	  9.3%
Thr (T)  15	  5.4%
Trp (W)   2	  0.7%
Tyr (Y)   7	  2.5%
Val (V)  18	  6.4%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 29
Total number of positively charged residues (Arg + Lys): 22

Atomic composition:

Carbon      C	      1372
Hydrogen    H	      2183
Nitrogen    N	       339
Oxygen      O	       396
Sulfur      S	        18

Formula: C1372H2183N339O396S18
Total number of atoms: 4308

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    21430
Abs 0.1% (=1 g/l)   0.706, assuming all pairs of Cys residues form cystines


Ext. coefficient    21430
Abs 0.1% (=1 g/l)   0.706, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 30.79
This classifies the protein as stable.



Aliphatic index: 106.71

Grand average of hydropathicity (GRAVY): 0.545