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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGNNTSRRSQ SQKFKNIPSI SAGSFSTMPV QHRGRRRRSK SIVGRAAQNA VLRSKEKTWI

70 80 90 100 110 120
VPLILLTLLV GWYFVNPNGY IKYGIFLSYP IPGTNPAQYG KGRLDIAFCL FYALFFTFCR

130 140 150 160 170 180
EFIMQEIIAR IGRHFNIRAP AKLRRFEEQA YTCLYFTVMG SWGLYVMKQT PMWFFNTDAF

190 200 210 220 230 240
WEEYPHFYHV GSFKAFYLIE AAYWIQQALV LILQLEKPRK DFKELVVHHI ITLLLIGLSY

250 260 270 280 290 300
YFHFTWIGLA VFITMDTSDI WLALSKCLNY VNTVIVYPIF VIFVFVWIYM RHYLNFKIMW

310 320 330 340 350 360
AVWGTMRTIN SFDLDWAAEQ YKCWISRDVT LILLTALQLV NIYWLILILR IGYRAFTTND

370 380
THDERSEDED EEVSDEKSSA KKND


References and documentation are available.

Number of amino acids: 384 Molecular weight: 45335.85 Theoretical pI: 9.29
Amino acid composition: 
Ala (A) 24 6.2% Arg (R) 23 6.0% Asn (N) 16 4.2% Asp (D) 14 3.6% Cys (C) 5 1.3% Gln (Q) 13 3.4% Glu (E) 17 4.4% Gly (G) 18 4.7% His (H) 9 2.3% Ile (I) 35 9.1% Leu (L) 37 9.6% Lys (K) 19 4.9% Met (M) 10 2.6% Phe (F) 29 7.6% Pro (P) 12 3.1% Ser (S) 22 5.7% Thr (T) 22 5.7% Trp (W) 14 3.6% Tyr (Y) 22 5.7% Val (V) 23 6.0% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 31 Total number of positively charged residues (Arg + Lys): 42 Atomic composition: Carbon C 2123 Hydrogen H 3193 Nitrogen N 533 Oxygen O 542 Sulfur S 15 Formula: C2123H3193N533O542S15 Total number of atoms: 6406 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 110030 Abs 0.1% (=1 g/l) 2.427, assuming all pairs of Cys residues form cystines Ext. coefficient 109780 Abs 0.1% (=1 g/l) 2.421, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 44.61 This classifies the protein as unstable. Aliphatic index: 96.74 Grand average of hydropathicity (GRAVY): 0.087