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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGNQSLVVLT ESKGEYENET ELPVKKSSRD NNIGESLTAT AFTQSEDEMV DSNQKWQNPN

70 80 90 100 110 120
YFKYAWQEYL FIFTCMISQL LNQAGTTQTL SIMNILSDSF GSEGNSKSWL MASFPLVSGS

130 140 150 160 170 180
FILISGRLGD IYGLKKMLLV GYVLVIIWSL ICGITKYSGS DTFFIISRAF QGLGIAFVLP

190 200 210 220 230 240
NVLGIIGNIY VGGTFRKNIV ISFVGAMAPI GATLGCLFAG LIGTEDPKQW PWAFYAYSIA

250 260 270 280 290 300
AFINFVLSIY AIPSTIPTNI HHFSMDWIGS VLGVIGLILL NFVWNQAPIS GWNQAYIIVI

310 320 330 340 350 360
LIISVIFLVV FIIYEIRFAK TPLLPRAVIK DRHMIQIMLA LFFGWGSFGI FTFYYFQFQL

370 380 390 400 410 420
NIRQYTALWA GGTYFMFLIW GIIAALLVGF TIKNVSPSVF LFFSMVAFNV GSIMASVTPV

430 440 450 460 470 480
HETYFRTQLG TMIILSFGMD LSFPASSIIF SDNLPMEYQG MAGSLVNTVV NYSMSLCLGM

490 500 510 520 530 540
GATVETQVNS DGKHLLKGYR GAQYLGIGLA SLACMISGLY MVESFIKGRR ARAAAEYDCT


VA


References and documentation are available.

Number of amino acids: 542 Molecular weight: 59983.18 Theoretical pI: 6.95
Amino acid composition: 
Ala (A) 38 7.0% Arg (R) 13 2.4% Asn (N) 25 4.6% Asp (D) 13 2.4% Cys (C) 6 1.1% Gln (Q) 20 3.7% Glu (E) 17 3.1% Gly (G) 49 9.0% His (H) 5 0.9% Ile (I) 58 10.7% Leu (L) 54 10.0% Lys (K) 17 3.1% Met (M) 21 3.9% Phe (F) 41 7.6% Pro (P) 16 3.0% Ser (S) 48 8.9% Thr (T) 29 5.4% Trp (W) 12 2.2% Tyr (Y) 24 4.4% Val (V) 36 6.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 30 Total number of positively charged residues (Arg + Lys): 30 Atomic composition: Carbon C 2791 Hydrogen H 4263 Nitrogen N 665 Oxygen O 749 Sulfur S 27 Formula: C2791H4263N665O749S27 Total number of atoms: 8495 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 102135 Abs 0.1% (=1 g/l) 1.703, assuming all pairs of Cys residues form cystines Ext. coefficient 101760 Abs 0.1% (=1 g/l) 1.696, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 32.63 This classifies the protein as stable. Aliphatic index: 106.86 Grand average of hydropathicity (GRAVY): 0.565