ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGQIQYSDKY FDDTFEYRHV VLPPEVAKLL PKNRILSESE WRAIGVQQSR GWVHYAIHRP 

        70         80 
EPHIMLFRRP LNYQQEHQAQ IAK 

References and documentation are available.

Number of amino acids: 83

Molecular weight: 9987.41

Theoretical pI: 9.10

Amino acid composition: 
Ala (A)   5	  6.0%
Arg (R)   7	  8.4%
Asn (N)   2	  2.4%
Asp (D)   3	  3.6%
Cys (C)   0	  0.0%
Gln (Q)   8	  9.6%
Glu (E)   6	  7.2%
Gly (G)   3	  3.6%
His (H)   5	  6.0%
Ile (I)   6	  7.2%
Leu (L)   6	  7.2%
Lys (K)   4	  4.8%
Met (M)   2	  2.4%
Phe (F)   3	  3.6%
Pro (P)   6	  7.2%
Ser (S)   4	  4.8%
Thr (T)   1	  1.2%
Trp (W)   2	  2.4%
Tyr (Y)   5	  6.0%
Val (V)   5	  6.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 9
Total number of positively charged residues (Arg + Lys): 11

Atomic composition:

Carbon      C	       454
Hydrogen    H	       692
Nitrogen    N	       130
Oxygen      O	       122
Sulfur      S	         2

Formula: C454H692N130O122S2
Total number of atoms: 1400

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    18450
Abs 0.1% (=1 g/l)   1.847

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 68.89
This classifies the protein as unstable.



Aliphatic index: 79.88

Grand average of hydropathicity (GRAVY): -0.730