ProtParam
User-provided sequence:
10 20 30 40 50 60
MGQKSSKVHI TKTDRAILEV KRSKDEIHKF TRRTDNLILV EKSQLKDLIR KNPENYKSNM
70 80 90 100 110 120
KVRFLLKRIH YQEHLLQQAS DQLINLENMV STLEFKMVEK QFINGLKNGN EILKKLNKEF
130 140 150 160 170 180
SNVDELMDDV QDQIAYQNEI NETLSRSLVG TSNYEDDLDK ELDALESELN PEKMNNAKVA
190 200 210 220
NMPSTEGLPS LPQGEQTEQK EREEFATEER SDTKEPLALL S
References and
documentation are available.
Number of amino acids: 221
Molecular weight: 25637.93
Theoretical pI: 5.24
Total number of negatively charged residues (Asp + Glu): 41
Total number of positively charged residues (Arg + Lys): 33
Atomic composition:
Carbon C 1111
Hydrogen H 1815
Nitrogen N 313
Oxygen O 366
Sulfur S 7
Formula: C
1111H
1815N
313O
366S
7
Total number of atoms: 3612
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 5960
Abs 0.1% (=1 g/l) 0.232
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 53.26
This classifies the protein as unstable.
Aliphatic index: 83.80
Grand average of hydropathicity (GRAVY): -0.899