ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGQLLSHPLT EKTIEYNEYK NNQASTGIVP RFYNCVGSMQ GYRLTQEDAH LIRNENSVVY 

        70         80         90        100        110        120 
VRFFNPFIDK YETLSLNVFA VFDGHGGDDC SKFLSGGRHH RDGNGSSNGN GEPNAGLIKW 

       130        140        150        160        170        180 
IAYSFENHHY TSTTNNDSSK FKRSFNTLEG LVSQIFKDAF ILQDEELYRH FANSSCGSTA 

       190        200        210        220        230        240 
VVACIINEES LYVANCGDSR CILSSKSNGI KTMSFDHKPQ HIGELIRIND NGGTVSLGRV 

       250        260        270        280        290        300 
GGVLALSRAF SDFQFKRGVT YPHRRTKLTN ITQNLTYGTP PQEAQVTVEP DVLMHKIDYS 

       310        320        330        340        350        360 
KDEFLVLACD GIWDIYNNKQ LIHFIKYHLV SGTKLDTIIT KLLDHGIAQA NSNTGVGFDN 

       370        380        390 
MTAIIVVLNR KGETLQDWFN KMKTRLERER GLV 

References and documentation are available.

Number of amino acids: 393

Molecular weight: 44175.71

Theoretical pI: 6.94

Amino acid composition: 
Ala (A)  17	  4.3%
Arg (R)  19	  4.8%
Asn (N)  31	  7.9%
Asp (D)  22	  5.6%
Cys (C)   7	  1.8%
Gln (Q)  14	  3.6%
Glu (E)  20	  5.1%
Gly (G)  33	  8.4%
His (H)  15	  3.8%
Ile (I)  26	  6.6%
Leu (L)  33	  8.4%
Lys (K)  22	  5.6%
Met (M)   6	  1.5%
Phe (F)  21	  5.3%
Pro (P)   9	  2.3%
Ser (S)  30	  7.6%
Thr (T)  26	  6.6%
Trp (W)   3	  0.8%
Tyr (Y)  15	  3.8%
Val (V)  24	  6.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 42
Total number of positively charged residues (Arg + Lys): 41

Atomic composition:

Carbon      C	      1956
Hydrogen    H	      3034
Nitrogen    N	       550
Oxygen      O	       594
Sulfur      S	        13

Formula: C1956H3034N550O594S13
Total number of atoms: 6147

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    39225
Abs 0.1% (=1 g/l)   0.888, assuming all pairs of Cys residues form cystines


Ext. coefficient    38850
Abs 0.1% (=1 g/l)   0.879, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 32.37
This classifies the protein as stable.



Aliphatic index: 80.59

Grand average of hydropathicity (GRAVY): -0.393