ProtParam
User-provided sequence:
10 20 30 40 50 60
MGRVRTKTVK RASKALIERY YPKLTLDFQT NKRLCDEIAT IQSKRLRNKI AGYTTHLMKR
70 80 90 100 110 120
IQKGPVRGIS FKLQEEERER KDQYVPEVSA LDLSRSNGVL NVDNQTSDLV KSLGLKLPLS
130
VINVSAQRDR RYRKRN
References and
documentation are available.
Number of amino acids: 136
Molecular weight: 15803.32
Theoretical pI: 10.51
Total number of negatively charged residues (Asp + Glu): 14
Total number of positively charged residues (Arg + Lys): 31
Atomic composition:
Carbon C 688
Hydrogen H 1163
Nitrogen N 217
Oxygen O 202
Sulfur S 3
Formula: C
688H
1163N
217O
202S
3
Total number of atoms: 2273
Extinction coefficients:
This protein does not contain any Trp residues. Experience shows that
this could result in more than 10% error in the computed extinction coefficient.
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 7450
Abs 0.1% (=1 g/l) 0.471, assuming all pairs of Cys residues form cystines
Ext. coefficient 7450
Abs 0.1% (=1 g/l) 0.471, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 47.07
This classifies the protein as unstable.
Aliphatic index: 88.82
Grand average of hydropathicity (GRAVY): -0.794