ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGRYSVKRYK TKRRTRDLDL IYNDLSTKES VQKLLNQPLD ETKPGLGQHY CIHCAKYMET 

        70         80         90        100        110        120 
AIALKTHLKG KVHKRRVKEL RGVPYTQEVS DAAAGYNLNK FLNRVQEITQ SVGPEKESNE 

       130        140        150        160 
ALLKEHLDST LANVKTTEPT LPWAAADAEA NTAAVTEAES TASAST 

References and documentation are available.

Number of amino acids: 166

Molecular weight: 18516.95

Theoretical pI: 8.98

Amino acid composition: 
Ala (A)  18	 10.8%
Arg (R)   9	  5.4%
Asn (N)   8	  4.8%
Asp (D)   7	  4.2%
Cys (C)   2	  1.2%
Gln (Q)   6	  3.6%
Glu (E)  14	  8.4%
Gly (G)   7	  4.2%
His (H)   5	  3.0%
Ile (I)   4	  2.4%
Leu (L)  17	 10.2%
Lys (K)  16	  9.6%
Met (M)   2	  1.2%
Phe (F)   1	  0.6%
Pro (P)   6	  3.6%
Ser (S)  10	  6.0%
Thr (T)  16	  9.6%
Trp (W)   1	  0.6%
Tyr (Y)   7	  4.2%
Val (V)  10	  6.0%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 21
Total number of positively charged residues (Arg + Lys): 25

Atomic composition:

Carbon      C	       807
Hydrogen    H	      1312
Nitrogen    N	       234
Oxygen      O	       256
Sulfur      S	         4

Formula: C807H1312N234O256S4
Total number of atoms: 2613

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    16055
Abs 0.1% (=1 g/l)   0.867, assuming all pairs of Cys residues form cystines


Ext. coefficient    15930
Abs 0.1% (=1 g/l)   0.860, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 39.62
This classifies the protein as stable.



Aliphatic index: 77.65

Grand average of hydropathicity (GRAVY): -0.689