ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGSDGDKKKK FIVAGSVSGF LVIMVVSVAV VTSKHSPKDD ENHIRKTTKA VQAVCAPTDF 

        70         80         90        100        110        120 
KDTCVNSLMG ASPDSDDPVD LIKLGFKVTI KSINESLEKA SGDIKAKADK NPEAKGAFEL 

       130        140        150        160        170        180 
CEKLMIDAID DLKKCMDHGF SVDQIEVFVE DLRVWLSGSI AFQQTCMDSF GEIKSNLMQD 

       190        200        210        220        230        240 
MLKIFKTSRE LSSNSLAMVT RISTLIPNSN LTGLTGALAK YARKLLSTED SIPTWVGPEA 

       250        260        270        280        290        300 
RRLMAAQGGG PGPVKANAVV AQDGTGQFKT ITDALNAVPK GNKVPFIIHI KEGIYKEKVT 

       310        320        330        340        350        360 
VTKKMPHVTF IGDGPNKTLI TGSLNFGIGK VKTFLTATIT IEGDHFTAKN IGIENTAGPE 

       370        380        390        400        410        420 
GGQAVALRVS ADYAVFHSCQ IDGHQDTLYV HSHRQFYRDC TVSGTVDFIF GDAKCILQNC 

       430        440        450        460        470        480 
KIVVRKPNKG QTCMVTAQGR SNVRESTGLV LHGCHITGDP AYIPMKSVNK AYLGRPWKEF 

       490        500        510        520        530        540 
SRTIIMKTTI DDVIDPAGWL PWSGDFALKT LYYAEHMNTG PGSNQAQRVK WPGIKKLTPQ 

       550        560 
DALLYTGDRF LRGDTWIPQT QVPYTAKV 

References and documentation are available.

Number of amino acids: 568

Molecular weight: 61886.22

Theoretical pI: 8.87

Amino acid composition: 
Ala (A)  42	  7.4%
Arg (R)  18	  3.2%
Asn (N)  21	  3.7%
Asp (D)  39	  6.9%
Cys (C)  11	  1.9%
Gln (Q)  20	  3.5%
Glu (E)  20	  3.5%
Gly (G)  48	  8.5%
His (H)  13	  2.3%
Ile (I)  40	  7.0%
Leu (L)  38	  6.7%
Lys (K)  51	  9.0%
Met (M)  15	  2.6%
Phe (F)  23	  4.0%
Pro (P)  26	  4.6%
Ser (S)  36	  6.3%
Thr (T)  45	  7.9%
Trp (W)   7	  1.2%
Tyr (Y)  11	  1.9%
Val (V)  44	  7.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 59
Total number of positively charged residues (Arg + Lys): 69

Atomic composition:

Carbon      C	      2751
Hydrogen    H	      4393
Nitrogen    N	       747
Oxygen      O	       820
Sulfur      S	        26

Formula: C2751H4393N747O820S26
Total number of atoms: 8737

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    55515
Abs 0.1% (=1 g/l)   0.897, assuming all pairs of Cys residues form cystines


Ext. coefficient    54890
Abs 0.1% (=1 g/l)   0.887, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 26.39
This classifies the protein as stable.



Aliphatic index: 83.42

Grand average of hydropathicity (GRAVY): -0.190