ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGSLVHVKEA TVITPSDQTP SSVLSLSALD SQLFLRFTIE YLLVYPPVSD PEYSLSGRLK 

        70         80         90        100        110        120 
SALSRALVPY FPFSGRVREK PDGGGGLEVN CRGQGALFLE AVSDILTCLD FQKPPRHVTS 

       130        140        150        160        170        180 
WRKLLSLHVI DVLAGAPPLV VQLTWLRDGG AALAVGVNHC VSDGIGSAEF LTLFAELSKD 

       190        200        210        220        230        240 
SLSQTELKRK HLWDRQLLMP SPIRDSLSHP EFNRVPDLCG FVNRFNAERL VPTSVVFERQ 

       250        260        270        280        290        300 
KLNELKKLAS RLGEFNSKHT SFEVLSAHVW RSWARSLNLP SNQVLKLLFS VNIRDRVKPS 

       310        320        330        340        350        360 
LPSGFYGNAF VVGCAQTTVK DLTEKGLSYA TMLVKQAKER VGDEYVRSVV EAVSKERASP 

       370        380        390        400        410        420 
DSVGVLILSQ WSRLGLEKLD FGLGKPVHVG SVCCDRYCLL LPIPEQNDAV KVMVAVPSSS 

       430 
VDTYENLVTS PNA 

References and documentation are available.

Number of amino acids: 433

Molecular weight: 47658.89

Theoretical pI: 8.53

Amino acid composition: 
Ala (A)  26	  6.0%
Arg (R)  26	  6.0%
Asn (N)  14	  3.2%
Asp (D)  21	  4.8%
Cys (C)   8	  1.8%
Gln (Q)  13	  3.0%
Glu (E)  23	  5.3%
Gly (G)  27	  6.2%
His (H)   9	  2.1%
Ile (I)   9	  2.1%
Leu (L)  60	 13.9%
Lys (K)  22	  5.1%
Met (M)   4	  0.9%
Phe (F)  18	  4.2%
Pro (P)  26	  6.0%
Ser (S)  47	 10.9%
Thr (T)  17	  3.9%
Trp (W)   6	  1.4%
Tyr (Y)   9	  2.1%
Val (V)  48	 11.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 44
Total number of positively charged residues (Arg + Lys): 48

Atomic composition:

Carbon      C	      2140
Hydrogen    H	      3412
Nitrogen    N	       584
Oxygen      O	       622
Sulfur      S	        12

Formula: C2140H3412N584O622S12
Total number of atoms: 6770

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    46910
Abs 0.1% (=1 g/l)   0.984, assuming all pairs of Cys residues form cystines


Ext. coefficient    46410
Abs 0.1% (=1 g/l)   0.974, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.65
This classifies the protein as stable.



Aliphatic index: 100.30

Grand average of hydropathicity (GRAVY): -0.010