ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGSRRYDSRT TIFSPEGRLY QVEYALESIS HAGTAIGIMA SDGIVLAAER KVTSTLLEQD 

        70         80         90        100        110        120 
TSTEKLYKLN DKIAVAVAGL TADAEILINT ARIHAQNYLK TYNEDIPVEI LVRRLSDIKQ 

       130        140        150        160        170        180 
GYTQHGGLRP FGVSFIYAGY DDRYGYQLYT SNPSGNYTGW KAISVGANTS AAQTLLQMDY 

       190        200        210        220        230        240 
KDDMKVDDAI ELALKTLSKT TDSSALTYDR LEFATIRKGA NDGEVYQKIF KPQEIKDILV 

       250 
KTGITKKDED EEADEDMK 

References and documentation are available.

Number of amino acids: 258

Molecular weight: 28714.26

Theoretical pI: 5.06

Amino acid composition: 
Ala (A)  24	  9.3%
Arg (R)  12	  4.7%
Asn (N)   8	  3.1%
Asp (D)  22	  8.5%
Cys (C)   0	  0.0%
Gln (Q)  10	  3.9%
Glu (E)  17	  6.6%
Gly (G)  18	  7.0%
His (H)   3	  1.2%
Ile (I)  20	  7.8%
Leu (L)  22	  8.5%
Lys (K)  19	  7.4%
Met (M)   5	  1.9%
Phe (F)   5	  1.9%
Pro (P)   5	  1.9%
Ser (S)  17	  6.6%
Thr (T)  22	  8.5%
Trp (W)   1	  0.4%
Tyr (Y)  16	  6.2%
Val (V)  12	  4.7%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 39
Total number of positively charged residues (Arg + Lys): 31

Atomic composition:

Carbon      C	      1268
Hydrogen    H	      2014
Nitrogen    N	       338
Oxygen      O	       410
Sulfur      S	         5

Formula: C1268H2014N338O410S5
Total number of atoms: 4035

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    29340
Abs 0.1% (=1 g/l)   1.022

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 30.46
This classifies the protein as stable.



Aliphatic index: 86.28

Grand average of hydropathicity (GRAVY): -0.436