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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGSSVYIMVE LAIAVLAILG NVLVCWAVWI NSNLQNVTNF FVVSLAAADI AVGVLAIPFA

70 80 90 100 110 120
ITISTGFCAA CHGCLFIACF VLVLTQSSIF SLLAIAIDRY IAIRIPLRYN GLVTGMKAKG

130 140 150 160 170 180
IIAICWVLSF AIGLTPMLGW NNCSQTDENS TKTCGEGRVT CLFEDVVPMN YMVYYNFFAF

190 200 210 220 230 240
VLLPLLLMLA IYLRIFLAAR RQLKQMESQP LPGERTRSTL QKEVHAAKSL AIIVGLFALC

250 260 270 280 290 300
WLPLHIINCF TFFCSTCQHA PPWLMYLAII LSHSNSVVNP FIYAYRIREF RQTFRKIIRT

310 320 330 340 350 360
HVLRRQEPFR AGGSSAWALA AHSTEGEQVS LRLNGHPLGV WANGSAPHSG RRPNGYTLGP

370 380 390 400 410
GGGGSTQGSP GDVELLTQEH QEGQEHPGLG DHLAQGRVGT ASWSSEFAPS


References and documentation are available.

Number of amino acids: 410 Molecular weight: 44882.34 Theoretical pI: 8.68
Amino acid composition: 
Ala (A) 40 9.8% Arg (R) 21 5.1% Asn (N) 17 4.1% Asp (D) 6 1.5% Cys (C) 13 3.2% Gln (Q) 16 3.9% Glu (E) 16 3.9% Gly (G) 34 8.3% His (H) 12 2.9% Ile (I) 31 7.6% Leu (L) 47 11.5% Lys (K) 7 1.7% Met (M) 9 2.2% Phe (F) 22 5.4% Pro (P) 19 4.6% Ser (S) 30 7.3% Thr (T) 21 5.1% Trp (W) 9 2.2% Tyr (Y) 11 2.7% Val (V) 29 7.1% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 22 Total number of positively charged residues (Arg + Lys): 28 Atomic composition: Carbon C 2042 Hydrogen H 3178 Nitrogen N 546 Oxygen O 550 Sulfur S 22 Formula: C2042H3178N546O550S22 Total number of atoms: 6338 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 66640 Abs 0.1% (=1 g/l) 1.485, assuming all pairs of Cys residues form cystines Ext. coefficient 65890 Abs 0.1% (=1 g/l) 1.468, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 37.93 This classifies the protein as stable. Aliphatic index: 104.46 Grand average of hydropathicity (GRAVY): 0.403