ProtParam
User-provided sequence:
10 20 30 40 50 60
MGSSVYIMVE LAIAVLAILG NVLVCWAVWI NSNLQNVTNF FVVSLAAADI AVGVLAIPFA
70 80 90 100 110 120
ITISTGFCAA CHGCLFIACF VLVLTQSSIF SLLAIAIDRY IAIRIPLRYN GLVTGMKAKG
130 140 150 160 170 180
IIAICWVLSF AIGLTPMLGW NNCSQTDENS TKTCGEGRVT CLFEDVVPMN YMVYYNFFAF
190 200 210 220 230 240
VLLPLLLMLA IYLRIFLAAR RQLKQMESQP LPGERTRSTL QKEVHAAKSL AIIVGLFALC
250 260 270 280 290 300
WLPLHIINCF TFFCSTCQHA PPWLMYLAII LSHSNSVVNP FIYAYRIREF RQTFRKIIRT
310 320 330 340 350 360
HVLRRQEPFR AGGSSAWALA AHSTEGEQVS LRLNGHPLGV WANGSAPHSG RRPNGYTLGP
370 380 390 400 410
GGGGSTQGSP GDVELLTQEH QEGQEHPGLG DHLAQGRVGT ASWSSEFAPS
References and
documentation are available.
Number of amino acids: 410
Molecular weight: 44882.34
Theoretical pI: 8.68
Total number of negatively charged residues (Asp + Glu): 22
Total number of positively charged residues (Arg + Lys): 28
Atomic composition:
Carbon C 2042
Hydrogen H 3178
Nitrogen N 546
Oxygen O 550
Sulfur S 22
Formula: C
2042H
3178N
546O
550S
22
Total number of atoms: 6338
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 66640
Abs 0.1% (=1 g/l) 1.485, assuming all pairs of Cys residues form cystines
Ext. coefficient 65890
Abs 0.1% (=1 g/l) 1.468, assuming all Cys residues are reduced
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 37.93
This classifies the protein as stable.
Aliphatic index: 104.46
Grand average of hydropathicity (GRAVY): 0.403