ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGTHIDINNL GGDTSRGNES KPLARQSSLY SLTFDELQST LGEPGKDFGS MNMDELLKNI 

        70         80         90        100        110        120 
WTAEDTQAFM TTTSSVAAPG PSGFVPGGNG LQRQGSLTLP RTLSQKTVDE VWKYLNSKEG 

       130        140        150        160        170        180 
SNGNTGTDAL ERQQTLGEMT LEDFLLRAGV VKEDNTQQNE NSSSGFYANN GAAGLEFGFG 

       190        200        210        220        230        240 
QPNQNSISFN GNNSSMIMNQ APGLGLKVGG TMQQQQQPHQ QQLQQPHQRL PPTIFPKQAN 

       250        260        270        280        290        300 
VTFAAPVNMV NRGLFETSAD GPANSNMGGA GGTVTATSPG TSSAENNTWS SPVPYVFGRG 

       310        320        330        340        350        360 
RRSNTGLEKV VERRQKRMIK NRESAARSRA RKQAYTLELE AEIESLKLVN QDLQKKQAEI 

       370        380        390 
MKTHNSELKE FSKQPPLLAK RQCLRRTLTG PW 

References and documentation are available.

Number of amino acids: 392

Molecular weight: 42727.58

Theoretical pI: 9.04

Amino acid composition: 
Ala (A)  26	  6.6%
Arg (R)  21	  5.4%
Asn (N)  31	  7.9%
Asp (D)  12	  3.1%
Cys (C)   1	  0.3%
Gln (Q)  32	  8.2%
Glu (E)  25	  6.4%
Gly (G)  39	  9.9%
His (H)   4	  1.0%
Ile (I)   9	  2.3%
Leu (L)  35	  8.9%
Lys (K)  20	  5.1%
Met (M)  12	  3.1%
Phe (F)  14	  3.6%
Pro (P)  21	  5.4%
Ser (S)  34	  8.7%
Thr (T)  31	  7.9%
Trp (W)   4	  1.0%
Tyr (Y)   5	  1.3%
Val (V)  16	  4.1%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 37
Total number of positively charged residues (Arg + Lys): 41

Atomic composition:

Carbon      C	      1836
Hydrogen    H	      2932
Nitrogen    N	       550
Oxygen      O	       600
Sulfur      S	        13

Formula: C1836H2932N550O600S13
Total number of atoms: 5931

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    29450
Abs 0.1% (=1 g/l)   0.689, assuming all pairs of Cys residues form cystines


Ext. coefficient    29450
Abs 0.1% (=1 g/l)   0.689, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 50.10
This classifies the protein as unstable.



Aliphatic index: 62.24

Grand average of hydropathicity (GRAVY): -0.744