ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGTKTKKTLF NVDEQMKAIA AQFETLQILN EKGEVVNEAA MPELSDDQLK ELMRRMVYTR 

        70         80         90        100        110        120 
VLDQRSISLN RQGRLGFYAP TAGQEASQLA SHFALEAEDF ILPGYRDVPQ LVWHGLPLYQ 

       130        140        150        160        170        180 
AFLFSRGHFM GNQMPENVNA LAPQIIIGAQ IIQTAGVALG MKLRGKKSVA ITYTGDGGAS 

       190        200        210        220        230        240 
QGDFYEGMNF AGAFKAPAIF VVQNNRYAIS TPVEKQSAAK TVAQKAVAAG IYGIQVDGMD 

       250        260        270        280        290        300 
PLAVYAATAF ARERAVNGEG PTLIETLTFR YGPHTMAGDD PTRYRTKDIE NEWEQKDPIV 

       310        320        330        340        350        360 
RFRAFLENKG LWSQEVEEKV IEEAKEDIKQ AIAKADQAPK QKVTDLMEIM YEKMPYNLAE 

       370 
QYEIYKEKES K 

References and documentation are available.

Number of amino acids: 371

Molecular weight: 41441.26

Theoretical pI: 5.52

Amino acid composition: 
Ala (A)  44	 11.9%
Arg (R)  17	  4.6%
Asn (N)  14	  3.8%
Asp (D)  17	  4.6%
Cys (C)   0	  0.0%
Gln (Q)  25	  6.7%
Glu (E)  32	  8.6%
Gly (G)  27	  7.3%
His (H)   4	  1.1%
Ile (I)  22	  5.9%
Leu (L)  26	  7.0%
Lys (K)  26	  7.0%
Met (M)  14	  3.8%
Phe (F)  16	  4.3%
Pro (P)  16	  4.3%
Ser (S)  12	  3.2%
Thr (T)  19	  5.1%
Trp (W)   3	  0.8%
Tyr (Y)  15	  4.0%
Val (V)  22	  5.9%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 49
Total number of positively charged residues (Arg + Lys): 43

Atomic composition:

Carbon      C	      1849
Hydrogen    H	      2906
Nitrogen    N	       498
Oxygen      O	       555
Sulfur      S	        14

Formula: C1849H2906N498O555S14
Total number of atoms: 5822

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    38850
Abs 0.1% (=1 g/l)   0.937

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 35.85
This classifies the protein as stable.



Aliphatic index: 79.51

Grand average of hydropathicity (GRAVY): -0.376