ProtParam
User-provided sequence:
10 20 30 40 50 60
MGTSIVNLNQ KIELPPIQVL FESLNRENET KPHFEERRLY QPNPSFVPRT NIAVGSPVNP
70 80 90 100 110 120
VPVSSPVFFI GPSPQRSIQN HNAIMTQNIR QYPVIYNNNR EVISTGERNY IITVGGPPVT
130 140 150 160 170 180
SSQPEYEHIS TPNFYQEQRL AQPHPVNESM MIGGYTNPQP ISISRGKMLS GNISTNSVRG
190 200 210 220 230 240
SNNGYSAKEK KHKAHGKRSN LPKATVSILN KWLHEHVNNP YPTVQEKREL LAKTGLTKLQ
250 260 270
ISNWFINARR RKIFSGQNDA NNFRRKFSSS TNLAKF
References and
documentation are available.
Number of amino acids: 276
Molecular weight: 31257.38
Theoretical pI: 10.23
Total number of negatively charged residues (Asp + Glu): 17
Total number of positively charged residues (Arg + Lys): 34
Atomic composition:
Carbon C 1384
Hydrogen H 2186
Nitrogen N 410
Oxygen O 408
Sulfur S 5
Formula: C
1384H
2186N
410O
408S
5
Total number of atoms: 4393
Extinction coefficients:
Extinction coefficients are in units of M
-1 cm
-1, at 280 nm measured in water.
Ext. coefficient 24410
Abs 0.1% (=1 g/l) 0.781
Estimated half-life:
The N-terminal of the sequence considered is M (Met).
The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Instability index:
The instability index (II) is computed to be 56.64
This classifies the protein as unstable.
Aliphatic index: 72.36
Grand average of hydropathicity (GRAVY): -0.718