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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGTSIVNLNQ KIELPPIQVL FESLNRENET KPHFEERRLY QPNPSFVPRT NIAVGSPVNP

70 80 90 100 110 120
VPVSSPVFFI GPSPQRSIQN HNAIMTQNIR QYPVIYNNNR EVISTGERNY IITVGGPPVT

130 140 150 160 170 180
SSQPEYEHIS TPNFYQEQRL AQPHPVNESM MIGGYTNPQP ISISRGKMLS GNISTNSVRG

190 200 210 220 230 240
SNNGYSAKEK KHKAHGKRSN LPKATVSILN KWLHEHVNNP YPTVQEKREL LAKTGLTKLQ

250 260 270
ISNWFINARR RKIFSGQNDA NNFRRKFSSS TNLAKF


References and documentation are available.

Number of amino acids: 276 Molecular weight: 31257.38 Theoretical pI: 10.23
Amino acid composition: 
Ala (A) 10 3.6% Arg (R) 18 6.5% Asn (N) 31 11.2% Asp (D) 1 0.4% Cys (C) 0 0.0% Gln (Q) 15 5.4% Glu (E) 16 5.8% Gly (G) 15 5.4% His (H) 8 2.9% Ile (I) 21 7.6% Leu (L) 15 5.4% Lys (K) 16 5.8% Met (M) 5 1.8% Phe (F) 11 4.0% Pro (P) 24 8.7% Ser (S) 27 9.8% Thr (T) 15 5.4% Trp (W) 2 0.7% Tyr (Y) 9 3.3% Val (V) 17 6.2% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 17 Total number of positively charged residues (Arg + Lys): 34 Atomic composition: Carbon C 1384 Hydrogen H 2186 Nitrogen N 410 Oxygen O 408 Sulfur S 5 Formula: C1384H2186N410O408S5 Total number of atoms: 4393 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 24410 Abs 0.1% (=1 g/l) 0.781 Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 56.64 This classifies the protein as unstable. Aliphatic index: 72.36 Grand average of hydropathicity (GRAVY): -0.718