ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGYLFQETLS SNPKTPIVVD DDNELGLMAV RLANAAAFPM VLKAALELGV FDTLYAAASR 

        70         80         90        100        110        120 
TDSFLSPYEI ASKLPTTPRN PEAPVLLDRM LRLLASYSMV KCGKALSGKG ERVYRAEPIC 

       130        140        150        160        170        180 
RFFLKDNIQD IGSLASQVIV NFDSVFLNTW AQLKDVVLEG GDAFGRAHGG MKLFDYMGTD 

       190        200        210        220        230        240 
ERFSKLFNQT GFTIAVVKKA LEVYEGFKGV KVLVDVGGGV GNTLGVVTSK YPNIKGINFD 

       250        260        270        280        290        300 
LTCALAQAPS YPGVEHVAGD MFVDVPTGDA MILKRILHDW TDEDCVKILK NCWKSLPENG 

       310        320        330        340        350        360 
KVVVIELVTP DEAENGDINA NIAFDMDMLM FTQCSGGKER SRAEFEALAA ASGFTHCKFV 

       370 
CQAYHCWIIE FCK 

References and documentation are available.

Number of amino acids: 373

Molecular weight: 40869.15

Theoretical pI: 5.21

Amino acid composition: 
Ala (A)  35	  9.4%
Arg (R)  13	  3.5%
Asn (N)  16	  4.3%
Asp (D)  25	  6.7%
Cys (C)  10	  2.7%
Gln (Q)   8	  2.1%
Glu (E)  21	  5.6%
Gly (G)  30	  8.0%
His (H)   5	  1.3%
Ile (I)  17	  4.6%
Leu (L)  36	  9.7%
Lys (K)  24	  6.4%
Met (M)  12	  3.2%
Phe (F)  22	  5.9%
Pro (P)  15	  4.0%
Ser (S)  19	  5.1%
Thr (T)  18	  4.8%
Trp (W)   4	  1.1%
Tyr (Y)  10	  2.7%
Val (V)  33	  8.8%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 46
Total number of positively charged residues (Arg + Lys): 37

Atomic composition:

Carbon      C	      1835
Hydrogen    H	      2870
Nitrogen    N	       474
Oxygen      O	       537
Sulfur      S	        22

Formula: C1835H2870N474O537S22
Total number of atoms: 5738

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient    37525
Abs 0.1% (=1 g/l)   0.918, assuming all pairs of Cys residues form cystines


Ext. coefficient    36900
Abs 0.1% (=1 g/l)   0.903, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 22.87
This classifies the protein as stable.



Aliphatic index: 90.46

Grand average of hydropathicity (GRAVY): 0.083