ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MGYQPKIGIS KTMIGCLGLC ALPALPLNAK EVLGAPKVEP IEILTVHGQQ YRRATTMTKP 

        70         80         90        100        110        120 
GEAIISMAEI EEMQATTFAE VIDDMAGAHI DGGTRSGGER INVWGFGETE DFNVYVDNAP 

       130        140        150        160        170        180 
VGFEQYRYGS FFLDPDLIKR VEVIKGAHDV RSGNGGFGGA MYVVTKSADD FLKYDQSVGA 

       190        200        210        220        230        240 
RVKASYASNN DAQSYTGTVY GRANQQLSGL LHFTRRDAQD VTLANGEAFE YSGYEQNNYL 

       250        260        270        280        290        300 
GKVDYEQGDH QLMLSVTHYL DEGRKPWANR RGPMPAISDF NIRKYGSYEQ ALYATTAYNT 

       310        320        330        340        350        360 
YEDNTWSANY RYSPSNPLID TQIVVSHSAN ARHWIRPPIA WEKMTVSVGN FGHESWLDYK 

       370        380        390        400        410        420 
RDYIDINNLS VVGAHEITAG LQFRSLDRTS LVFNKSYEKN PEKNFGWYTP YYQPEGRQDT 

       430        440        450        460        470        480 
YAAYLRDAIS LTDDLTITPS LRYDFVYSVG KPNIAPDYND IAAGHDYSST HHSGFSPRLG 

       490        500        510        520        530        540 
VDYQLTPNTR VNFDYAYSLQ APVVDEIYAV QYAKASITAT SRDIEVERLH AFKLGLINQQ 

       550        560        570        580        590        600 
TDLFADQDAL STQITVYANL GRDDIAQRRG AKSDPNQAIQ SGYTNLDGYE IYGADLESQY 

       610        620        630        640        650        660 
RYQDFFSDLA VSWLQGEHRG SLKDSLGEDE YLANIAPLDI QLRVGMYITD SISVAWQGTW 

       670        680        690        700        710        720 
YDAQDNVPEG DIFNAESPSE NYFLQNIYLA YEPLDSLKGL SIRLMAKNLT NQQVTPFLSD 

       730 
GIPAPGRDVR LSLAYEF 

References and documentation are available.

Number of amino acids: 737

Molecular weight: 82590.62

Theoretical pI: 4.84

Amino acid composition: 
Ala (A)  64	  8.7%
Arg (R)  37	  5.0%
Asn (N)  39	  5.3%
Asp (D)  56	  7.6%
Cys (C)   2	  0.3%
Gln (Q)  37	  5.0%
Glu (E)  39	  5.3%
Gly (G)  58	  7.9%
His (H)  15	  2.0%
Ile (I)  42	  5.7%
Leu (L)  57	  7.7%
Lys (K)  25	  3.4%
Met (M)  12	  1.6%
Phe (F)  26	  3.5%
Pro (P)  32	  4.3%
Ser (S)  52	  7.1%
Thr (T)  41	  5.6%
Trp (W)  10	  1.4%
Tyr (Y)  52	  7.1%
Val (V)  41	  5.6%
Pyl (O)   0	  0.0%
Sec (U)   0	  0.0%

 (B)   0	  0.0%
 (Z)   0	  0.0%
 (X)   0	  0.0%


Total number of negatively charged residues (Asp + Glu): 95
Total number of positively charged residues (Arg + Lys): 62

Atomic composition:

Carbon      C	      3687
Hydrogen    H	      5577
Nitrogen    N	       989
Oxygen      O	      1149
Sulfur      S	        14

Formula: C3687H5577N989O1149S14
Total number of atoms: 11416

Extinction coefficients:

Extinction coefficients are in units of  M-1 cm-1, at 280 nm measured in water.

Ext. coefficient   132605
Abs 0.1% (=1 g/l)   1.606, assuming all pairs of Cys residues form cystines


Ext. coefficient   132480
Abs 0.1% (=1 g/l)   1.604, assuming all Cys residues are reduced

Estimated half-life:

The N-terminal of the sequence considered is M (Met).

The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro).
                            >20 hours (yeast, in vivo).
                            >10 hours (Escherichia coli, in vivo).


Instability index:

The instability index (II) is computed to be 34.10
This classifies the protein as stable.



Aliphatic index: 77.20

Grand average of hydropathicity (GRAVY): -0.459