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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MHCPICHHRA HVVYCAHCIN TSPSLLLKLK LDLILLKDEN KELNGKVEQI LNEAMNYDQL

70 80 90 100 110 120
DIKRMEKKKD PLMNSLMKLD VLRMKKNNNL IRHRIEQLNE RIYSKRNHIS ELKVEIDNYK

130 140 150 160 170 180
CYKVGTGTDK LREQVEISDA KNKLAQVSKI CESARDYKLN LLNNWFVIQK LQDNFQIPFA

190 200 210 220 230 240
IAFQPLISLK NFRILPLAIT NDSINIMWKY ISFFSDILMI KLPYTNKICE QPMFEFSDSI

250 260 270 280 290 300
QTVVQRLIKL IINILQICRH LKLVPSTPMD IPWLLDQYDV DGLFYNMVKR NKMKCRSVSL

310 320 330 340
YWTFGMLYSM VLDNMNNPQR GHPARRTAPP PTVTGPHDRW YVVG


References and documentation are available.

Number of amino acids: 344 Molecular weight: 40453.61 Theoretical pI: 9.33
Amino acid composition: 
Ala (A) 11 3.2% Arg (R) 18 5.2% Asn (N) 27 7.8% Asp (D) 20 5.8% Cys (C) 9 2.6% Gln (Q) 15 4.4% Glu (E) 14 4.1% Gly (G) 8 2.3% His (H) 10 2.9% Ile (I) 31 9.0% Leu (L) 41 11.9% Lys (K) 31 9.0% Met (M) 15 4.4% Phe (F) 11 3.2% Pro (P) 17 4.9% Ser (S) 18 5.2% Thr (T) 11 3.2% Trp (W) 5 1.5% Tyr (Y) 13 3.8% Val (V) 19 5.5% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 34 Total number of positively charged residues (Arg + Lys): 49 Atomic composition: Carbon C 1819 Hydrogen H 2914 Nitrogen N 496 Oxygen O 497 Sulfur S 24 Formula: C1819H2914N496O497S24 Total number of atoms: 5750 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 47370 Abs 0.1% (=1 g/l) 1.171, assuming all pairs of Cys residues form cystines Ext. coefficient 46870 Abs 0.1% (=1 g/l) 1.159, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 39.74 This classifies the protein as stable. Aliphatic index: 100.84 Grand average of hydropathicity (GRAVY): -0.282