Home  |  Contact

ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MHGPTSKAIS RNVRSVKRPR RAPRPVVSTQ AMNKLSNVTL SAEQEKLRER VLSFMRSNLS

70 80 90 100 110 120
QYKSDWKHPA MFVIQGDAGT GKSVILNSLF NEIQKLSQFS PSSEDILHGT HNYLVVNHPE

130 140 150 160 170 180
MLKLYIRISD SFKYISKSSL ERPTSLINNL QKRKVMADVV IVDEAHLLAT SKDAFKRFYG

190 200 210 220 230 240
ENHLKDLMSL CKVLVLVYDD KQALRMGSYW DEGSNNGATL KDFYNEIPPK SRDWYTLKQQ

250 260 270 280 290 300
FRVAAPQNVL NWIDQISVAG KIPPIESVLS KGNADCADDK IKNFDFKIWD DCGAMYEAIK

310 320 330 340 350 360
EKDRQYGQCR MLSTYDFPYR LDGKDYYVEC GDNFKVRWDR YTPREVTPWS ERCDTIDEVG

370 380 390 400 410 420
SVYTIQGFDL NYAGVILGRS IGYDAANDCI KLRPELYDDR AGFTKKKNIH NAEDVKQKII

430 440 450
MNSINVLLTR GVRGLYVYAY DPELRERLLR PSKK


References and documentation are available.

Number of amino acids: 454 Molecular weight: 52256.69 Theoretical pI: 9.11
Amino acid composition: 
Ala (A) 25 5.5% Arg (R) 31 6.8% Asn (N) 25 5.5% Asp (D) 35 7.7% Cys (C) 7 1.5% Gln (Q) 16 3.5% Glu (E) 22 4.8% Gly (G) 23 5.1% His (H) 8 1.8% Ile (I) 27 5.9% Leu (L) 39 8.6% Lys (K) 38 8.4% Met (M) 11 2.4% Phe (F) 15 3.3% Pro (P) 19 4.2% Ser (S) 36 7.9% Thr (T) 16 3.5% Trp (W) 7 1.5% Tyr (Y) 23 5.1% Val (V) 31 6.8% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 57 Total number of positively charged residues (Arg + Lys): 69 Atomic composition: Carbon C 2326 Hydrogen H 3663 Nitrogen N 649 Oxygen O 685 Sulfur S 18 Formula: C2326H3663N649O685S18 Total number of atoms: 7341 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 73145 Abs 0.1% (=1 g/l) 1.400, assuming all pairs of Cys residues form cystines Ext. coefficient 72770 Abs 0.1% (=1 g/l) 1.393, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 36.56 This classifies the protein as stable. Aliphatic index: 82.00 Grand average of hydropathicity (GRAVY): -0.544