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ProtParam

User-provided sequence:

        10         20         30         40         50         60 
MHISLPTRNK SYFRIRTRTY QIGLYHSDSS PIRDISVLHL LIATLCTIFF PIFFSLSKVQ

70 80 90 100 110 120
VVQWQGTTIS KNCIALTMSF PLNAIPGMYL IIAFPRLQTV IPLQRNTPVR ITKSVIVKGA

130
VSVPRISSPM H


References and documentation are available.

Number of amino acids: 131 Molecular weight: 14827.68 Theoretical pI: 11.01
Amino acid composition: 
Ala (A) 5 3.8% Arg (R) 9 6.9% Asn (N) 4 3.1% Asp (D) 2 1.5% Cys (C) 2 1.5% Gln (Q) 6 4.6% Glu (E) 0 0.0% Gly (G) 4 3.1% His (H) 4 3.1% Ile (I) 17 13.0% Leu (L) 12 9.2% Lys (K) 5 3.8% Met (M) 4 3.1% Phe (F) 7 5.3% Pro (P) 10 7.6% Ser (S) 14 10.7% Thr (T) 11 8.4% Trp (W) 1 0.8% Tyr (Y) 4 3.1% Val (V) 10 7.6% Pyl (O) 0 0.0% Sec (U) 0 0.0% (B) 0 0.0% (Z) 0 0.0% (X) 0 0.0%
Total number of negatively charged residues (Asp + Glu): 2 Total number of positively charged residues (Arg + Lys): 14 Atomic composition: Carbon C 681 Hydrogen H 1098 Nitrogen N 182 Oxygen O 175 Sulfur S 6 Formula: C681H1098N182O175S6 Total number of atoms: 2142 Extinction coefficients: Extinction coefficients are in units of M-1 cm-1, at 280 nm measured in water. Ext. coefficient 11585 Abs 0.1% (=1 g/l) 0.781, assuming all pairs of Cys residues form cystines Ext. coefficient 11460 Abs 0.1% (=1 g/l) 0.773, assuming all Cys residues are reduced Estimated half-life: The N-terminal of the sequence considered is M (Met). The estimated half-life is: 30 hours (mammalian reticulocytes, in vitro). >20 hours (yeast, in vivo). >10 hours (Escherichia coli, in vivo). Instability index: The instability index (II) is computed to be 52.15 This classifies the protein as unstable. Aliphatic index: 112.29 Grand average of hydropathicity (GRAVY): 0.366